Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes (Q35804584)

10 August 2017

Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes (English)

1 reference

10 August 2017

1 reference

Brian Boer

1

1 reference

10 August 2017

Janel Kopp

2

1 reference

10 August 2017

Sunil Mallanna

3

1 reference

10 August 2017

Michelle Desler

4

1 reference

10 August 2017

Harini Chakravarthy

5

1 reference

10 August 2017

Phillip J Wilder

6

1 reference

10 August 2017

Cory Bernadt

7

1 reference

10 August 2017

Angie Rizzino

8

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10 August 2017

language of work or name

English

0 references

publication date

25 February 2007

1 reference

10 August 2017

Nucleic Acids Research

1 reference

10 August 2017

35

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10 August 2017

6

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10 August 2017

1773-1786

1 reference

describes a project that uses

10 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1874607/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells

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Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells

11 July 2018

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Differential activity of the FGF-4 enhancer in F9 and P19 embryonal carcinoma cells

11 July 2018

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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

11 July 2018

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Differentiation of mouse embryonic stem cells after RNA interference-mediated silencing of OCT4 and Nanog

11 July 2018

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Core transcriptional regulatory circuitry in human embryonic stem cells

11 July 2018

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Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

11 July 2018

1 reference

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Oct-3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus

11 July 2018

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Transcriptional regulation of nanog by OCT4 and SOX2.

11 July 2018

1 reference

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Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells

11 July 2018

1 reference

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SoxB transcription factors specify neuroectodermal lineage choice in ES cells

11 July 2018

1 reference

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The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells

11 July 2018

1 reference

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Regulation of the FGF-4 gene by a complex distal enhancer that functions in part as an enhanceosome

11 July 2018

1 reference

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A PCR primer bank for quantitative gene expression analysis

11 July 2018

1 reference

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Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers

11 July 2018

1 reference

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Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Multipotent cell lineages in early mouse development depend on SOX2 function

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Transfection of embryonal carcinoma cells at high efficiency using liposome-mediated transfection

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Embryonic stem cells provide a powerful and versatile model system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Effects of B-Myb on gene transcription: phosphorylation-dependent activity ans acetylation by p300

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Structural analyses of the UTF1 gene encoding a transcriptional coactivator expressed in pluripotent embryonic stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Synergistic, p160 coactivator-dependent enhancement of estrogen receptor function by CARM1 and p300.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Identification of the transactivation domain of the transcription factor Sox-2 and an associated co-activator.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Appearance of nuclear protease activity after embryonal carcinoma cells undergo differentiation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

11 July 2018

Regulatory squelching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Cryptic promoter activity within the backbone of a plasmid commonly used to prepare promoter/reporter gene constructs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Requirement of FGF-4 for postimplantation mouse development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Differential expression of two homologous and clustered oncogenes, Hst1 and Int-2, during differentiation of F9 cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Transcriptional regulation of the murine k-FGF gene in embryonic cell lines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Isolation, characterization, and differential expression of the murine Sox-2 promoter

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

Embryonal carcinoma cell growth and differentiation Production of and response to molecules with transforming growth factor activity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1874607

The co-activator p300 associates physically with and can mediate the action of the distal enhancer of the FGF-4 gene

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17324942

12 December 2020

inferred from PubMed ID database lookup

Transcription factor Sox-2 inhibits co-activator stimulated transcription

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17324942

12 December 2020

inferred from PubMed ID database lookup

Expression of the K-fgf protooncogene is repressed during differentiation of F9 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17324942

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKM059

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

17324942

1 reference