Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice (Q36071796)

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English	Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Ectonucleotide triphosphate diphosphohydrolase-1 (CD39) mediates resistance to occlusive arterial thrombus formation after vascular injury in mice (English)

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Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Zachary M Huttinger

1

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12 August 2017

Michael W Milks

2

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12 August 2017

Michael S Nickoli

3

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12 August 2017

William L Aurand

4

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12 August 2017

Lawrence C Long

5

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12 August 2017

Debra G Wheeler

6

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12 August 2017

Karen M Dwyer

7

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Europe PubMed Central

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12 August 2017

Anthony J F d'Apice

8

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12 August 2017

Simon C Robson

9

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12 August 2017

Peter J Cowan

10

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12 August 2017

Richard J Gumina

11

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12 August 2017

language of work or name

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publication date

18 May 2012

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12 August 2017

The American Journal of Pathology

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12 August 2017

181

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12 August 2017

1

1 reference

Europe PubMed Central

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12 August 2017

322-333

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Europe PubMed Central

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12 August 2017

Transgenic swine: expression of human CD39 protects against myocardial injury

1 reference

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2 October 2017

Transgenic over expression of ectonucleotide triphosphate diphosphohydrolase-1 protects against murine myocardial ischemic injury.

1 reference

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2 October 2017

The antithrombotic activity of EP224283, a neutralizable dual factor Xa inhibitor/glycoprotein IIbIIIa antagonist, exceeds that of the coadministered parent compounds

1 reference

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2 October 2017

Evidence of platelet activation at medically used hypothermia and mechanistic data indicating ADP as a key mediator and therapeutic target

1 reference

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2 October 2017

Adenosine and its receptors in the heart: Regulation, retaliation and adaptation

1 reference

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2 October 2017

Inhibition of vascular ectonucleotidase activities by the pro-drugs ticlopidine and clopidogrel favours platelet aggregation.

1 reference

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2 October 2017

Purinergic signaling: a fundamental mechanism in neutrophil activation

1 reference

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2 October 2017

Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis.

1 reference

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2 October 2017

NTPDase1 governs P2X7-dependent functions in murine macrophages

1 reference

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2 October 2017

The ecto-nucleotidase NTPDase1 differentially regulates P2Y1 and P2Y2 receptor-dependent vasorelaxation

1 reference

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2 October 2017

From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease

1 reference

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2 October 2017

NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Murine strain differences in hemostasis and thrombosis and tissue factor pathway inhibitor

1 reference

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2 October 2017

Characterization of the A2B adenosine receptor from mouse, rabbit, and dog.

1 reference

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2 October 2017

Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury

1 reference

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2 October 2017

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

1 reference

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2 October 2017

Physiological roles for ecto-5'-nucleotidase (CD73).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

P2 receptors in cardiovascular regulation and disease

1 reference

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2 October 2017

Nucleotide receptor signaling in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

New insights into the regulation of inflammation by adenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Tissue factor encryption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Role of platelets in the pathophysiology of acute coronary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Current concepts of the pathogenesis of the acute coronary syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Suppression of ATP diphosphohydrolase/CD39 in human vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Receptors for purines and pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Distribution of P2Y receptor subtypes on haematopoietic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Identification and characterization of CD39/vascular ATP diphosphohydrolase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

The human platelet ADP receptor activates Gi2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryptamine release in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

2 October 2017

Adenosine diphosphate as a mediator of platelet aggregation in vivo

1 reference

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2 October 2017

P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice

1 reference

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27 July 2018

Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

27 July 2018

Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

27 July 2018

Adenosine regulates tissue factor expression on endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

27 July 2018

Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

27 July 2018

Asymmetry of vascular responses of perfused rabbit carotid artery to intraluminal and abluminal vasoactive stimuli

1 reference

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27 July 2018

Autocrine Purinergic Receptor Signaling Is Essential for Macrophage Chemotaxis

1 reference

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23 September 2018

Tissue factor and thrombosis: The clot starts here.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

A new role for the A2b adenosine receptor in regulating platelet function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Whole blood aggregation, coagulation, and markers of platelet activation in diet-induced diabetic C57BL/6J mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Direct treatment of mouse or human blood with soluble 5'-nucleotidase inhibits platelet aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Raised levels of CD39 in leucocytosis result in marked inhibition of ADP-induced platelet aggregation via rapid ADP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Gene expression profiling for the identification of G-protein coupled receptors in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Molecular regulation of platelet-dependent thrombosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Flow cytometric detection of activated mouse integrin alphaIIbbeta3 with a novel monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Defective platelet activation in G alpha(q)-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3388153

23 September 2018

Forskolin and prostacyclin inhibit fluoride induced platelet activation and protein kinase C dependent responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

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Increased Platelet Binding to Circulating Monocytes in Acute Coronary Syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dipyridamole inhibition of adenosine metabolism in human blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of CD39 to plaque instability and thrombus formation in directional atherectomy specimens from patients with stable and unstable angina pectoris

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A standardized 'in vivo' model for the study of experimental arterial thrombosis: description of a method

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/22613024

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.AJPATH.2012.03.024

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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