Block and tackle: CTLA4Ig takes on lupus (Q36088049)

12 August 2017

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title

Block and tackle: CTLA4Ig takes on lupus (English)

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12 August 2017

A Davidson

1

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author name string

B Diamond

series ordinal

2

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12 August 2017

D Wofsy

series ordinal

3

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12 August 2017

D Daikh

series ordinal

4

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12 August 2017

publication date

1 January 2005

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12 August 2017

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12 August 2017

volume

14

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12 August 2017

issue

3

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12 August 2017

page(s)

197-203

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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

12 August 2017

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The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

21 January 2018

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New perspectives of CD28-B7-mediated T cell costimulation

21 January 2018

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Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

21 January 2018

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A new member of the immunoglobulin superfamily--CTLA-4

21 January 2018

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 January 2018

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CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

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CTLA4 mediates antigen-specific apoptosis of human T cells

21 January 2018

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

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CTLA-4: new insights into its biological function and use in tumor immunotherapy

21 January 2018

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Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

21 January 2018

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The roles of the new negative T cell costimulatory pathways in regulating autoimmunity

21 January 2018

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Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

21 January 2018

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Ligation of B7 with CD28/CTLA-4 on T cells results in CD40 ligand expression, interleukin-4 secretion and efficient help for antibody production by B cells

21 January 2018

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New TCR transgenic model for tracking allospecific CD4 T-cell activation and tolerance in vivo

21 January 2018

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Functional responses and costimulator dependence of memory CD4+ T cells.

21 January 2018

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Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells

21 January 2018

1 reference

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CTLA4Ig inhibits T cell-dependent B-cell maturation in murine systemic lupus erythematosus

21 January 2018

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Cutting edge: reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide

21 January 2018

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The effect of CD28/B7 blockade on alloreactive T and B cells after liver cell transplantation.

21 January 2018

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Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

21 January 2018

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

21 January 2018

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CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

CTLA-4-Ig regulates tryptophan catabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

21 January 2018

The B7-CD28 superfamily

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.

21 January 2018

1 reference

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CD28-independent induction of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 January 2018

1 reference

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The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens

21 January 2018

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Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

21 January 2018

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Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+ T cells.

21 January 2018

1 reference

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CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis

21 January 2018

1 reference

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Genetic background determines the requirement for B7 costimulation in induction of autoimmunity.

21 January 2018

1 reference

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Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection

21 January 2018

1 reference

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Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts.

21 January 2018

1 reference

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

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Treatment of murine lupus with CTLA4Ig

21 January 2018

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Autoantibody responses and pathology regulated by B7-1 and B7-2 costimulation in MRL/lpr lupus.

21 January 2018

1 reference

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Prevention of renal damage in murine lupus nephritis by CTLA-4Ig and cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

CTLA4Ig prevents initiation but not evolution of anti-phospholipid syndrome in NZW/BXSB mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs.

21 January 2018

1 reference

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The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade

21 January 2018

1 reference

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Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway1

21 January 2018

1 reference

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Interaction Between ICOS-B7RP1 and B7-CD28 Costimulatory Pathways in Alloimmune Responses In Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Bcl-2 protection of islet allografts is unmasked by costimulation blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

The immune tolerance network and rheumatic disease: immune tolerance comes to the clinic

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Activation requirements for the induction of CD4+CD25+ T cell suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Minimal Model for the Mechanism of Antibody Induction and Paralysis by Antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

Mechanism of Action of Transmembrane Activator and Calcium Modulator Ligand Interactor-Ig in Murine Systemic Lupus Erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F0961203305LU2136OA

10.1191/0961203305LU2136OA

21 January 2018

Identifiers

DOI

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12 August 2017

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