The 1027th target candidate in stroke: Will NADPH oxidase hold up? (Q36112519)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22625431%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

The 1027th target candidate in stroke: Will NADPH oxidase hold up? (English)

1 reference

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2 February 2020

author

Christoph Kleinschnitz

6

1 reference

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2 February 2020

author name string

Kim A Radermacher

1

1 reference

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2 February 2020

Kirstin Wingler

2

1 reference

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2 February 2020

Pamela Kleikers

3

1 reference

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2 February 2020

Sebastian Altenhöfer

4

1 reference

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2 February 2020

Johannes Jr Hermans

5

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2 February 2020

Harald Hhw Schmidt

7

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2 February 2020

publication date

24 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22625431%20AND%20SRC:MED&resulttype=core&format=json

Experimental & translational stroke medicine

2 February 2020

published in

1 reference

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2 February 2020

volume

4

1 reference

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2 February 2020

issue

1

1 reference

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2 February 2020

page(s)

11

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Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine (VAS2870).

2 February 2020

cites work

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Role of neuroimaging in promoting long‐term recovery from ischemic stroke

2 October 2017

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Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

2 October 2017

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NOX4: A Guilty Party in Stroke Damage

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Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

2 October 2017

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NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

2 October 2017

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2 October 2017

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Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries.

2 October 2017

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Identification of renox, an NAD(P)H oxidase in kidney

2 October 2017

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NAD(P)H oxidase: role in cardiovascular biology and disease

2 October 2017

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Recommendations for standards regarding preclinical neuroprotective and restorative drug development

2 October 2017

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Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors

2 October 2017

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Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

2 October 2017

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Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production

2 October 2017

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Long-term monitoring of post-stroke plasticity after transient cerebral ischemia in mice using in vivo and ex vivo diffusion tensor MRI

2 July 2018

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Apocynin improves outcome in experimental stroke with a narrow dose range

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Stroke mortality and trends from 1990 to 2006 in 39 countries from Europe and Central Asia: implications for control of high blood pressure.

2 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Translational stroke research of the combination of thrombolysis and antioxidant therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Gene transfer of NAD(P)H oxidase inhibitor to the vascular adventitia attenuates medial smooth muscle hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Increased NADPH-oxidase activity and Nox4 expression during chronic hypertension is associated with enhanced cerebral vasodilatation to NADPH in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Translation-linked mRNA destabilization accompanying serum-induced Nox4 expression in human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Nox4 acts as a switch between differentiation and proliferation in preadipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

4-(2-Aminoethyl)benzenesulfonyl fluoride attenuates tumor-necrosis-factor-alpha-induced blood-brain barrier opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Apocynin, NADPH oxidase, and vascular cells: a complex matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

NADPH oxidase activity and function are profoundly greater in cerebral versus systemic arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Effect of the reperfusion after cerebral ischemia in neonatal rats using MRI monitoring.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2040-7378-4-11

Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3403875

Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22625431

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NXY-059 for the treatment of acute ischemic stroke

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22625431

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/2040-7378-4-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22625431%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22625431%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

22625431

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22625431%20AND%20SRC:MED&resulttype=core&format=json