Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis (Q36186747)

12 August 2017

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis (English)

1 reference

12 August 2017

Rik van der Kant

8

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Karim L Kreft

Karim L Kreft

2

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John J. Priatel

John J Priatel

12

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Rusung Tan

Rusung Tan

11

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Sjaak Neefjes

Jacques Neefjes

13

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author name string

Marvin M van Luijn

1

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12 August 2017

Marlieke L Jongsma

3

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12 August 2017

Steven W Mes

4

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12 August 2017

Annet F Wierenga-Wolf

5

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12 August 2017

Marjan van Meurs

6

1 reference

12 August 2017

Marie-José Melief

7

1 reference

12 August 2017

Lennert Janssen

9

1 reference

12 August 2017

Hans Janssen

10

1 reference

12 August 2017

Jon D Laman

14

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12 August 2017

Rogier Q Hintzen

15

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12 August 2017

language of work or name

English

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publication date

29 March 2015

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12 August 2017

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12 August 2017

138

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12 August 2017

Pt 6

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12 August 2017

1531-1547

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4614123/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The diabetes susceptibility gene Clec16a regulates mitophagy

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1 October 2017

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From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A.

1 October 2017

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The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

1 October 2017

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Drosophila Golgi membrane protein Ema promotes autophagosomal growth and function.

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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

1 October 2017

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Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex

1 October 2017

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A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation

1 October 2017

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Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

1 October 2017

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Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic

1 October 2017

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Regulation of major histocompatibility complex class II genes

1 October 2017

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A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution

1 October 2017

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The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation.

1 October 2017

1 reference

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Multiple common variants for celiac disease influencing immune gene expression

1 October 2017

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Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis

1 October 2017

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Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning

1 October 2017

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Signalling through C-type lectin receptors: shaping immune responses

1 October 2017

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1 October 2017

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Vitamin effects on the immune system: vitamins A and D take centre stage

1 October 2017

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Detecting shared pathogenesis from the shared genetics of immune-related diseases

1 October 2017

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Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells

1 October 2017

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Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis

1 October 2017

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Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event

1 October 2017

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MHC class II molecules on the move for successful antigen presentation

1 October 2017

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Risk alleles for multiple sclerosis identified by a genomewide study

1 October 2017

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A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

1 October 2017

1 reference

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1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells

1 October 2017

1 reference

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Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes

1 October 2017

1 reference

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Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis

1 October 2017

1 reference

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The C-type lectin-like domain superfamily

1 October 2017

1 reference

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Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

1 October 2017

1 reference

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Rab conversion as a mechanism of progression from early to late endosomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

Self- and nonself-recognition by C-type lectins on dendritic cells

1 October 2017

1 reference

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Epitope spreading in immune-mediated diseases: implications for immunotherapy

1 October 2017

1 reference

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The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments

1 October 2017

1 reference

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Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS.

1 October 2017

1 reference

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Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments

1 October 2017

1 reference

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Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes

1 October 2017

1 reference

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Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

1 October 2017

1 reference

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The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis.

2 July 2018

1 reference

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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614123

Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus

23 September 2018

1 reference

12 December 2020

Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus

1 reference

12 December 2020

Human monocytes and neutrophils store transforming growth factor-alpha in a subpopulation of cytoplasmic granules

1 reference

12 December 2020

Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients

1 reference

12 December 2020

Identifiers

DOI

10.1093/BRAIN/AWV080

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

25823473

1 reference