TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1. (Q36280725)

13 August 2017

TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1. (English)

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13 August 2017

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5

Lieve Umans

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Abhishek Sharma

Abhishek Sharma

2

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Danny Huylebroeck

Danny Huylebroeck

9

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Shunichi Takeda

Shunichi Takeda

8

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Yves Pommier

7

Yves Pommier

1 reference

13 August 2017

Zhihong Zeng

1

1 reference

13 August 2017

Limei Ju

3

1 reference

13 August 2017

Junko Murai

4

1 reference

13 August 2017

Lieve Umans

5

1 reference

13 August 2017

Liesbeth Vermeire

6

1 reference

13 August 2017

Keith W Caldecott

10

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13 August 2017

Sherif F El-Khamisy

11

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13 August 2017

language of work or name

English

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publication date

26 June 2012

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13 August 2017

Nucleic Acids Research

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13 August 2017

40

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13 August 2017

17

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13 August 2017

8371-8380

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Creative Commons Attribution-NonCommercial 3.0 Unported

13 August 2017

start time

7 November 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair.

1 reference

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Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells

30 September 2017

1 reference

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TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-β signaling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

The PML nuclear bodies-associated protein TTRAP regulates ribosome biogenesis in nucleolar cavities upon proteasome inhibition.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1.

30 September 2017

1 reference

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To live or to die: a matter of processing damaged DNA termini in neurons

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

30 September 2017

1 reference

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A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks

30 September 2017

1 reference

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Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458563

Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin

29 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22740648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22740648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKS622

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22740648

1 reference