In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy (Q36314064)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

In vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Christoph Rader

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

D Shabat

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

U Pertl

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

R A Reisfeld

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

R A Lerner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

C F Barbas

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

language of work or name

English

0 references

publication date

12 June 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

98

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

7528-7533

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

Prodrug activation enzymes in cancer gene therapy

8 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Antibody-directed enzyme prodrug therapy (ADEPT): a review

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Developments with targeted enzymes in cancer therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Multiple event activation of a generic prodrug trigger by antibody catalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Antibody directed enzyme prodrug therapy (ADEPT): a review of the experimental and clinical considerations

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Etoposide: four decades of development of a topoisomerase II inhibitor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Cyclosporine delays host immune response to antibody enzyme conjugate in ADEPT.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Pharmacokinetics of anti-ganglioside GD2 mAb 14G2a in a phase I trial in pediatric cancer patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Clinical strategies for the treatment of neuroblastoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

The First Bagshawe lecture. Towards generating cytotoxic agents at cancer sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Toxicity of intraperitoneally administered antitumour drugs in athymic rats.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34702

Reconstructing Aldolase Antibodies to Alter Their Substrate Specificity and Turnover

29 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131187998

A phase I study of human/mouse chimeric antiganglioside GD2 antibody ch14.18 in patients with neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131187998

A phase I study of neuroblastoma with the anti-ganglioside GD2 antibody 14.G2a

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131187998

Cyclization-activated prodrugs. Basic carbamates of 4-hydroxyanisole

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131187998

Antibody-directed enzyme prodrug therapy: pharmacokinetics and plasma levels of prodrug and drug in a phase I clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.131187998

Natural killer cell-mediated eradication of neuroblastoma metastases to bone marrow by targeted interleukin-2 therapy

21 January 2018

1 reference

12 December 2020

Antibody response to murine anti-GD2 monoclonal antibodies: correlation with patient survival

1 reference

12 December 2020

Enhancement of the in vitro and in vivo antitumor activities of phosphorylated mitomycin C and etoposide derivatives by monoclonal antibody-alkaline phosphatase conjugates

1 reference

12 December 2020

Immunosuppressive properties and circulating life of Achromobacter glutaminase-asparaginase covalently attached to polyethylene glycol in man

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.131187998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11404472%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

11404472

1 reference