Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation (Q36382456)

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English	Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Wenkuan Xin

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Rupal P Soder

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Qiuping Cheng

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Eric S Rovner

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Georgi V Petkov

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

19 September 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

American Journal of Physiology - Cell Physiology

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Europe PubMed Central

PMC publication ID

13 August 2017

303

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

C1079-89

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca2+-activated K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Inhibition of phosphodiesterases relaxes detrusor smooth muscle via activation of the large-conductance voltage- and Ca²⁺-activated K⁺ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Role of potassium ion channels in detrusor smooth muscle function and dysfunction

1 reference

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30 September 2017

Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system

1 reference

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30 September 2017

Pharmacological activation of small conductance calcium-activated potassium channels with naphtho[1,2-d]thiazol-2-ylamine decreases guinea pig detrusor smooth muscle excitability and contractility

1 reference

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30 September 2017

Do β3-adrenergic receptors play a role in guinea pig detrusor smooth muscle excitability and contractility?

1 reference

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30 September 2017

Phosphodiesterase 4 inhibition attenuates persistent heart and lung injury by neonatal hyperoxia in rats.

1 reference

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30 September 2017

Large conductance Ca2+ -activated K+ channel activation with NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle

1 reference

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30 September 2017

PDEs create local domains of cAMP signaling.

1 reference

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30 September 2017

Phosphodiesterase (PDE) inhibitors in the treatment of lower urinary tract dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Large-conductance voltage- and Ca2+-activated K+ channels regulate human detrusor smooth muscle function

1 reference

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30 September 2017

Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions

1 reference

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30 September 2017

The BK potassium channel in the vascular smooth muscle and kidney: α- and β-subunits

1 reference

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30 September 2017

Detrusor overactivity is associated with downregulation of large-conductance calcium- and voltage-activated potassium channel protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Identification of large conductance calcium activated potassium channel accessory beta4 subunit in rat and mouse bladder smooth muscle

1 reference

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30 September 2017

Supramolecular assemblies and localized regulation of voltage-gated ion channels.

1 reference

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30 September 2017

Stimulation of beta3-adrenoceptors relaxes rat urinary bladder smooth muscle via activation of the large-conductance Ca2+-activated K+ channels

1 reference

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30 September 2017

Beta-adrenergic relaxation of mouse urinary bladder smooth muscle in the absence of large-conductance Ca2+-activated K+ channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signaling

1 reference

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30 September 2017

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity

1 reference

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30 September 2017

Overview of PDEs and their regulation

1 reference

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30 September 2017

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

1 reference

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30 September 2017

Diagnosis and management of patients with overactive bladder syndrome and abnormal detrusor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Integrative control of the lower urinary tract: preclinical perspective

1 reference

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30 September 2017

MaxiK channel partners: physiological impact

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

1 reference

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30 September 2017

Spontaneous activity of lower urinary tract smooth muscles: correlation between ion channels and tissue function

1 reference

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30 September 2017

Urinary bladder contraction and relaxation: physiology and pathophysiology

1 reference

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30 September 2017

Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder

1 reference

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30 September 2017

Describing bladder storage function: overactive bladder syndrome and detrusor overactivity

1 reference

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30 September 2017

Electrical properties of detrusor smooth muscles from the pig and human urinary bladder

1 reference

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30 September 2017

Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

30 September 2017

Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside

1 reference

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30 September 2017

mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope

1 reference

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30 September 2017

Voltage dependence of the coupling of Ca(2+) sparks to BK(Ca) channels in urinary bladder smooth muscle

1 reference

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30 September 2017

The calcium/calmodulin-dependent phosphodiesterase PDE1C down-regulates glucose-induced insulin secretion

1 reference

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30 September 2017

cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists

1 reference

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30 September 2017

The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4D3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

28 June 2018

Differential regulation of Ca2+-activated K+ channels by beta-adrenoceptors in guinea pig urinary bladder smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

28 June 2018

Regional difference in functional roles of cAMP and cGMP in lower urinary tract smooth muscle contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

28 June 2018

Selective, direct activation of high-conductance, calcium-activated potassium channels causes smooth muscle relaxation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Ionic basis for the regulation of spontaneous excitation in detrusor smooth muscle cells of the guinea-pig urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Identification and functional study of phosphodiesterases in rat urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Cyclic nucleotide phosphodiesterases in rabbit detrusor smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Low levels of K(ATP) channel activation decrease excitability and contractility of urinary bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3492835

21 September 2018

Effects of potassium channel modulators on human detrusor smooth muscle myogenic phasic contractile activity: potential therapeutic targets for overactive bladder

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

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Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphodiesterase type 5 inhibitors improve male lower urinary tract symptoms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve-evoked purinergic signalling suppresses action potentials, Ca2+ flashes and contractility evoked by muscarinic receptor activation in mouse urinary bladder smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of urinary bladder smooth muscle contractions by ryanodine receptors and BK and SK channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial clinical experience with the selective phosphodiesterase-I isoenzyme inhibitor vinpocetine in the treatment of urge incontinence and low compliance bladder

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of various phosphodiesterase-inhibitors, forskolin, and sodium nitroprusside on porcine detrusor smooth muscle tonic responses to muscarinergic stimulation and cyclic nucleotide levels in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle. I. Identification and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca(2+)-activated K+ channels regulate action potential repolarization in urinary bladder smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22992675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPCELL.00162.2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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