Therapeutic potential of targeting IL-17 and IL-23 in sepsis (Q36555432)

14 August 2017

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title

Therapeutic potential of targeting IL-17 and IL-23 in sepsis (English)

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14 August 2017

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2

Peter A Ward

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14 August 2017

Markus Bosmann

1

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14 August 2017

27 April 2012

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Clinical and translational medicine

14 August 2017

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14 August 2017

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14 August 2017

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14 August 2017

4

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Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Complement dependency of cardiomyocyte release of mediators during sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Functional specialization of interleukin-17 family members

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Profound lack of interleukin (IL)-12/IL-23p40 in neonates born early in gestation is associated with an increased risk of sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Innate IL-17-producing cells: the sentinels of the immune system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

IL-23 in the pathogenesis of rheumatoid arthritis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Functional roles for C5a receptors in sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Transforming growth factor-beta induces development of the T(H)17 lineage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Human IL-17: a novel cytokine derived from T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3552565

Protective effects of C5a blockade in sepsis

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F2001-1326-1-4

The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F2001-1326-1-4

The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F2001-1326-1-4

IL-23 neutralization protects mice from Gram-negative endotoxic shock

21 January 2018

1 reference

12 December 2020

Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production

1 reference

12 December 2020

A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses

1 reference

12 December 2020

Adverse functions of IL-17A in experimental sepsis

1 reference

12 December 2020

Signaling through the murine T cell receptor induces IL-17 production in the absence of costimulation, IL-23 or dendritic cells

1 reference

12 December 2020

Interleukin-17A plays a pivotal role in polymicrobial sepsis according to studies using IL-17A knockout mice

1 reference

12 December 2020

Identifiers

DOI

10.1186/2001-1326-1-4

1 reference

PMC publication ID

3552565

Dimensions Publication ID

14 August 2017

0 references

1 reference

PMC publication ID

3552565

14 August 2017

PubMed publication ID

23369364

1 reference

PMC publication ID

3552565