The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia. (Q36842360)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554387%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

review article

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title

The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia (English)

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31 December 2019

1 reference

4

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31 December 2019

author name string

Mikesch JH

1

1 reference

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31 December 2019

Steffen B

2

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31 December 2019

Berdel WE

3

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31 December 2019

Müller-Tidow C

5

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31 December 2019

publication date

7 June 2007

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31 December 2019

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31 December 2019

volume

21

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31 December 2019

issue

8

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31 December 2019

page(s)

1638-1647

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CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

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7 January 2021

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

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An LDL-receptor-related protein mediates Wnt signalling in mice

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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Casein kinase I transduces Wnt signals

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Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function

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Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

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A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes

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7 January 2021

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7 January 2021

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7 January 2021

The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos.

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7 January 2021

Regulation of the Wnt signaling pathway by disabled-2 (Dab2)

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7 January 2021

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7 January 2021

The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Identification of the haematopoietic stem cell niche and control of the niche size

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7 January 2021

Recent advances in defining the hematopoietic stem cell niche

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7 January 2021

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

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7 January 2021

Modulation of wingless signaling by Notch in Drosophila.

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Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

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Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

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7 January 2021

Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

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7 January 2021

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

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7 January 2021

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

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7 January 2021

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7 January 2021

Secreted antagonists of the Wnt signalling pathway

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7 January 2021

Methylation of p15 and p16 genes in acute promyelocytic leukemia: potential diagnostic and prognostic significance

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7 January 2021

Hypermethylation of gene promoters in hematological neoplasia

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7 January 2021

The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

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7 January 2021

DNA methylation of tumor suppressor genes in clinical remission predicts the relapse risk in acute myeloid leukemia.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

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7 January 2021

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

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7 January 2021

Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia

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7 January 2021

Akt participation in the Wnt signaling pathway through Dishevelled

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7 January 2021

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

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7 January 2021

Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: direct evidence of PI3K activation

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7 January 2021

Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable

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7 January 2021

Survival of acute myeloid leukemia cells requires PI3 kinase activation

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Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

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7 January 2021

Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation.

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Lymphoid Enhancer Factor-1 Links Two Hereditary Leukemia Syndromes through Core-binding Factor α Regulation of ELA2

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7 January 2021

LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia

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7 January 2021

Aberrant expression of beta-catenin discriminates acute myeloid leukaemia from acute lymphoblastic leukaemia.

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7 January 2021

Expression of beta-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis

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7 January 2021

An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells

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7 January 2021

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

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7 January 2021

SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice

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7 January 2021

Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family

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7 January 2021

Cloning and characterization of two promoters for the human HSAL2 gene and their transcriptional repression by the Wilms tumor suppressor gene product

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7 January 2021

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7 January 2021

SALL1 expression in the human pituitary-adrenal/gonadal axis

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7 January 2021

Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy

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7 January 2021

SALL4 is directly activated by TCF/LEF in the canonical Wnt signaling pathway

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7 January 2021

Inhibition of adipogenesis by Wnt signaling

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7 January 2021

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

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7 January 2021

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

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7 January 2021

Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue

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7 January 2021

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

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7 January 2021

A crosstalk between the Wnt and the adhesion-dependent signaling pathways governs the chemosensitivity of acute myeloid leukemia.

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7 January 2021

Wnt signaling regulates transendothelial migration of monocytes

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7 January 2021

The PI3 kinase-Akt pathway mediates Wnt3a-induced proliferation

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7 January 2021

Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.

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7 January 2021

Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated with poor clinical outcome

1 reference

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7 January 2021

PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021

Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021

Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021

Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the β-catenin signaling activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021

Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404732

7 January 2021