Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells (Q37408422)

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scientific article published on 06 July 2009

Language	Label	Description	Also known as
English	Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells	scientific article published on 06 July 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

0 references

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1 reference

based on heuristic

inferred from title

oxidative stress

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colon carcinoma

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based on heuristic

inferred from title

author name string

Melissa A Fath

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Anne R Diers

2

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Europe PubMed Central

PMC publication ID

20 August 2017

Nukhet Aykin-Burns

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Andrean L Simons

4

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Europe PubMed Central

PMC publication ID

20 August 2017

Lei Hua

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Douglas R Spitz

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

6 July 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Cancer Biology and Therapy

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

8

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Europe PubMed Central

PMC publication ID

20 August 2017

13

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Europe PubMed Central

PMC publication ID

20 August 2017

1228-1236

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Targeting heat shock protein 90 overrides the resistance of lung cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

6 September 2017

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

1 reference

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6 September 2017

Pyruvate protects mitochondria from oxidative stress in human neuroblastoma SK-N-SH cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

6 September 2017

Binding of the respiratory chain inhibitor antimycin to the mitochondrial bc1 complex: a new crystal structure reveals an altered intramolecular hydrogen-bonding pattern

1 reference

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6 September 2017

The thioredoxin reductase/thioredoxin system: novel redox targets for cancer therapy

1 reference

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6 September 2017

mtDNA mutations increase tumorigenicity in prostate cancer

1 reference

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Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease

1 reference

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6 September 2017

Protein measurement with the Folin phenol reagent

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6 September 2017

Bcl-XL Mutations Suppress Cellular Sensitivity to Antimycin A

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6 September 2017

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

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6 September 2017

Mitochondrial DNA in human malignancy.

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6 September 2017

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

6 September 2017

Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?

1 reference

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6 September 2017

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

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6 September 2017

Glucose regulation of hydroperoxide metabolism in rat intestinal cells. Stimulation of reduced nicotinamide adenine dinucleotide phosphate supply

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6 September 2017

Simple Isolation of Antimycin A 1 and Some of Its Toxicological Properties

1 reference

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6 September 2017

Cytotoxicity and metabolism of 4-hydroxy-2-nonenal and 2-nonenal in H2O2-resistant cell lines. Do aldehydic by-products of lipid peroxidation contribute to oxidative stress?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

6 September 2017

Mitochondrial Production of Superoxide Radical and Hydrogen Peroxide

1 reference

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6 September 2017

Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

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14 September 2017

Pyruvate reduces DNA damage during hypoxia and after reoxygenation in hepatocellular carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma cells but not in normal human astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

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In vitro search for synergy between flavonoids and epirubicin on multidrug-resistant cancer cells.

1 reference

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14 September 2017

A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

Non-nitro radiation sensitizers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

14 September 2017

2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

26 June 2018

Heat shock inactivates cellular antioxidant defenses against hydrogen peroxide: protection by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

26 June 2018

Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

2 September 2018

Pyruvate protection against endothelial cytotoxicity induced by blockade of glucose uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

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2 September 2018

2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771689

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Hypersensitization of tumor cells to glycolytic inhibitors

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2 September 2018

Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells.

1 reference

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2 September 2018

Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas

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12 December 2020

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Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

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https://pubmed.ncbi.nlm.nih.gov/19411865

12 December 2020

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Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19411865

12 December 2020

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Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19411865

12 December 2020

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The mitochondrial site of superoxide formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19411865

12 December 2020

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Structural factors of antimycin A molecule required for inhibitory action

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https://pubmed.ncbi.nlm.nih.gov/19411865

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The role of glucose in cellular defences against cytotoxicity of hydrogen peroxide in Chinese hamster ovary cells

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https://pubmed.ncbi.nlm.nih.gov/19411865

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A model of antimycin A binding based on structure-activity studies of synthetic antimycin A analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19411865

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Acute toxicity and cardio-respiratory effects of 2-deoxy-D-glucose: a promising radio sensitiser

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https://pubmed.ncbi.nlm.nih.gov/19411865

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Mitochondrial dysfunction in human colorectal cancer progression

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Identifiers

10.4161/CBT.8.13.8631

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

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