Nucleoside transporters: biological insights and therapeutic applications (Q38031634)

27 August 2017

title

Nucleoside transporters: biological insights and therapeutic applications (English)

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27 August 2017

Jung-Suk Choi

1

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27 August 2017

Anthony J Berdis

series ordinal

2

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27 August 2017

publication date

1 July 2012

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Future Medicinal Chemistry

27 August 2017

number of pages

18

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based on heuristic

inferred from page(s)

published in

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27 August 2017

volume

4

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27 August 2017

issue

11

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27 August 2017

page(s)

1461-1478

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Nucleoside transporters: molecular biology and implications for therapeutic development

27 August 2017

cites work

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Physiological and pharmacological roles of nucleoside transporter proteins

21 January 2018

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Physiological roles of vascular nucleoside transporters

21 January 2018

1 reference

The concentrative nucleoside transporter family, SLC28

21 January 2018

1 reference

Functional and molecular characteristics of Na(+)-dependent nucleoside transporters.

21 January 2018

1 reference

Nucleoside transporters: from scavengers to novel therapeutic targets

21 January 2018

1 reference

Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters

21 January 2018

1 reference

Alterations in adenosine triphosphate and energy charge in cultured endothelial and P388D1 cells after oxidant injury

21 January 2018

1 reference

21 January 2018

Adenosine transporters

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Nucleoside and nucleobase transport systems of mammalian cells

21 January 2018

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The A2B adenosine receptor protects against inflammation and excessive vascular adhesion

21 January 2018

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Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line

21 January 2018

1 reference

Mammalian nucleoside transporters

21 January 2018

1 reference

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs

21 January 2018

1 reference

The equilibrative nucleoside transporter family, SLC29

21 January 2018

1 reference

Functional characterization in yeast of genetic variants in the human equilibrative nucleoside transporter, ENT1

21 January 2018

1 reference

The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics

21 January 2018

1 reference

Molecular determinants of substrate selectivity in Na+-dependent nucleoside transporters

21 January 2018

1 reference

Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.

21 January 2018

1 reference

Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter

21 January 2018

1 reference

Role of CNT3 in the transepithelial flux of nucleosides and nucleoside-derived drugs

21 January 2018

1 reference

Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å

21 January 2018

1 reference

A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine

21 January 2018

1 reference

Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1

21 January 2018

1 reference

Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole

21 January 2018

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Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations

21 January 2018

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Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3).

21 January 2018

1 reference

Identification of cysteines involved in the effects of methanethiosulfonate reagents on human equilibrative nucleoside transporter 1.

21 January 2018

1 reference

Hypoxia regulates the adenosine transporter, mENT1, in the murine cardiomyocyte cell line, HL-1.

21 January 2018

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HIF-1-dependent repression of equilibrative nucleoside transporter (ENT) in hypoxia

21 January 2018

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The role of receptor structure in determining adenosine receptor activity

21 January 2018

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The effect of insulin on expression level of nucleoside transporters in diabetic rats.

21 January 2018

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Insulin and glucose induced changes in expression level of nucleoside transporters and adenosine transport in rat T lymphocytes

21 January 2018

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Differential effect of insulin and elevated glucose level on adenosine transport in rat B lymphocytes

21 January 2018

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Up-regulation of the high-affinity pyrimidine-preferring nucleoside transporter concentrative nucleoside transporter 1 by tumor necrosis factor-alpha and interleukin-6 in liver parenchymal cells

21 January 2018

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Nucleoside transport and its significance for anticancer drug resistance

21 January 2018

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Role of adenosine in delayed preconditioning of myocardium

21 January 2018

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Acute hypoxemia in humans enhances the neutrophil inflammatory response

21 January 2018

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Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line

21 January 2018

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Adenosine, adenosine receptors and myocardial protection: an updated overview

21 January 2018

1 reference

Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26

21 January 2018

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Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

21 January 2018

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Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism

21 January 2018

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Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia

21 January 2018

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Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency

21 January 2018

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Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation

21 January 2018

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Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

21 January 2018

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Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors

21 January 2018

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Functions of neuronal adenosine receptors

21 January 2018

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Cloned blood-brain barrier adenosine transporter is identical to the rat concentrative Na+ nucleoside cotransporter CNT2.

21 January 2018

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Distribution of mRNA encoding a nitrobenzylthioinosine-insensitive nucleoside transporter (ENT2) in rat brain

21 January 2018

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Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)

21 January 2018

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Nucleoside transporters are widely expressed in ovarian carcinoma effusions.

21 January 2018

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The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia

21 January 2018

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Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia

21 January 2018

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The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma.

21 January 2018

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Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

21 January 2018

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Gene-expression profiling reveals down-regulation of equilibrative nucleoside transporter 1 (ENT1) in Ara-C-resistant CCRF-CEM-derived cells.

21 January 2018

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Equilibrative nucleoside transporter 1 genotype, cytidine deaminase activity and age predict gemcitabine plasma clearance in patients with solid tumours

21 January 2018

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Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells

21 January 2018

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Kinetics of nucleoside uptake by the basolateral side of the sheep choroid plexus epithelium perfused in situ

21 January 2018

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Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines

21 January 2018

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Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors

21 January 2018

1 reference

Design, synthesis, and evaluation of 5'-S-aminoethyl-N(6)- azidobenzyl-5'-thioadenosine biotin conjugate: a bifunctional photoaffinity probe for the es nucleoside transporter

21 January 2018

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Dipyridamole, an underestimated vascular protective drug

21 January 2018

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Nucleoside transport inhibitors: structure-activity relationships for pyrimido[5,4-d]pyrimidine derivatives that potentiate pemetrexed cytotoxicity in the presence of α1-acid glycoprotein.

21 January 2018

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Studies of nucleoside transporters using novel autofluorescent nucleoside probes

21 January 2018

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Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'-fluorothymidine

21 January 2018

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A novel non-natural nucleoside that influences P-glycoprotein activity and mediates drug resistance

21 January 2018

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21 January 2018

Identifiers

DOI

10.4155/FMC.12.79

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27 August 2017

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