Anti-DNA antibodies, autoimmunity and the immunoglobulin repertoire (Q38218760)

31 August 2017

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title

Anti-DNA antibodies, autoimmunity and the immunoglobulin repertoire (English)

1 reference

31 August 2017

Barrett KJ

1

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31 August 2017

publication date

1 January 1989

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International Reviews of Immunology

31 August 2017

published in

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31 August 2017

volume

5

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31 August 2017

issue

1

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31 August 2017

page(s)

43-78

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Somatic generation of antibody diversity

31 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Regulation of genome rearrangement events during lymphocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Development of the primary antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Transgenic mice with immunoglobulin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Lambda chains and genes in inbred mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Linking of the human immunoglobulin VK and JKCK regions by chromosomal walking

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Physical map of the human immunoglobulin K locus and its implications for the mechanisms of VK-JK rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Organization and evolution of immunoglobulin VH gene subgroups

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

A novel family of variable region genes of the human immunoglobulin heavy chain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Early restriction of the human antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Human heavy-chain variable region gene family nonrandomly rearranged in familial chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

A new human immunoglobulin VH family preferentially rearranged in immature B-cell tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Evidence for a new murine immunoglobulin heavy chain variable region gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

One heavy chain variable region gene segment subfamily in the BALB/c mouse contains 500-1000 or more members

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

The T-cell-independent immune response to the hapten NP uses a large repertoire of heavy chain genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Diversity of germ-line immunoglobulin VH genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

The genetic basis of antibody production: a single heavy chain variable region gene encodes all molecules bearing the dominant anti-arsonate idiotype in the strain A mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Evolution of pseudogenes in the immunoglobulin VH-gene family of the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Human immunoglobulin variable region genes: a new VH sequence used to detect polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Immunoglobulin VH region genes of the mouse are organized in overlapping clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Immunoglobulin genes of different subgroups are interdigitated within the VK locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Dispersed human immunoglobulin kappa light-chain genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

The chicken B cell compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Developmentally controlled expression of immunoglobulin VH genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Adult B-cell repertoire is biased toward two heavy-chain variable-region genes that rearrange frequently in fetal pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Different joining region J elements of the murine kappa immunoglobulin light chain locus are used at markedly different frequencies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Preferential rearrangement of the immunoglobulin kappa chain joining region J kappa 1 and J kappa 2 segments in mouse spleen DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

VH-gene expression in murine lipopolysaccharide blasts distributes over the nine known VH-gene groups and may be random

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

VH gene family utilization is regulated by a locus outside of the VH region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Genotypic analysis of B cell colonies by in situ hybridization. Stoichiometric expression of three VH families in adult C57BL/6 and BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Genetics, expression, and function of idiotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Idiotype connectance in the immune system. II. A heavy chain variable region idiotope that dominates the antibody response to the p-azobenzenearsonate group is a minor idiotope in the response to trinitrophenyl group.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Several V genes participate in the early phenyloxazolone response in various combinations.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Molecular basis of a mouse strain-specific anti-hapten response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Genetic basis for expression of the idiotypic network. One unique Ig VH germline gene accounts for the major family of Ab1 and Ab3 (Ab1') antibodies of the GAT system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

V kappa and J kappa gene segments of A/J Ars-A antibodies: somatic recombination generates the essential arginine at the junction of the variable and joining regions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Single germline VH and V kappa genes encode predominating antibody variable regions elicited in strain A mice by immunization with p-azophenylarsonate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Evolution of antibody variable region structure during the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Complete amino acid sequence of heavy chain variable regions derived from two monoclonal anti-p-azophenylarsonate antibodies of BALB/c mice expressing the major cross-reactive idiotype of the A/J strain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Heavy chain variable region. Multiple gene segments encode anti-4-(hydroxy-3-nitro-phenyl)acetyl idiotypic antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Site-directed mutagenesis of an invariant amino acid residue at the variable-diversity segments junction of an antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Mutation drift and repertoire shift in the maturation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Somatic mutation in anti-phosphorylcholine antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

IgG antibodies to phosphorylcholine exhibit more diversity than their IgM counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Studies on the somatic instability of immunoglobulin genes in vivo and in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Activation of memory and virgin B cell clones in hyperimmune animals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Evolutionary and somatic selection of the antibody repertoire in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Antibody diversity: somatic hypermutation of rearranged VH genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Measurements of mutation rates in B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Immunologic and genetic factors in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Origins of anti-DNA autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

The role of somatic mutation of immunoglobulin genes in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

The genetic origin of autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Antibodies to polynucleotides in human sera: antigenic specificity and relation to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Reassessment of the clinical significance of native dna antibodies in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Anti-DNA autoantibody-producing hybridomas of normal human lymphoid cell origin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Rheumatoid factor secretion from human Leu-1+ B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Clonal analysis of the anti-DNA repertoire of murine B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Multispecific monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Avidity of anti-DNA antibodies in serum and IgG glomerular eluates from patients with systemic lupus erythematosus. Association of high avidity antinative DNA antibody with glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Distinct clonotypes of anti-DNA antibodies in mice with lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Binding of a monoclonal anti-DNA autoantibody to identical protein(s) present at the surface of several human cell types involved in lupus pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Idiotypic cross-reactions of monoclonal human lupus autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Normal mice express idiotypes related to autoantibody idiotypes of lupus mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Familial systemic lupus erythematosus. Presence of a cross-reactive idiotype in healthy family members

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Detection of cross-reactive anti-DNA antibody idiotypes on renal tissue-bound immunoglobulins from lupus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Parallel sets of autoantibodies in MRL-lpr/lpr mice. An anti-DNA, anti-SmRNP, anti-gp70 network

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Functional and molecular studies of V genes expressed in autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

V genes encoding autoantibodies: molecular and phenotypic characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Molecular aspects of murine systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

High frequency of autoantibodies bearing cross-reactive idiotopes among hybridomas using VH7183 genes prepared from normal and autoimmune murine strains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Studies of twins with systemic lupus erythematosus. A review of the literature and presentation of 12 additional sets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

A spontaneous rheumatoid arthritis-like disease in MRL/l mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Variable region genes for the immunoglobulin framework are assembled from small segments of DNA—A hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Expansion and functional activity of Ly-1+ B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

The role of clonal selection and somatic mutation in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830188909086989

10.3109/08830188909086989

21 January 2018

Identifiers

DOI

1 reference

31 August 2017

1 reference