Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants (Q38289065)

1 September 2017

title

Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants (English)

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1 September 2017

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11

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1 September 2017

Nobutaka Sakae

1

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1 September 2017

Nobuyuki Yamasaki

2

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1 September 2017

Kiyoyuki Kitaichi

3

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1 September 2017

Takaichi Fukuda

4

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1 September 2017

Mitsunori Yamada

5

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1 September 2017

Hiroo Yoshikawa

6

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1 September 2017

Takato Hiranita

7

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1 September 2017

Yoshiki Tatsumi

8

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1 September 2017

Jun-ichi Kira

9

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1 September 2017

Tsuneyuki Yamamoto

10

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1 September 2017

Keiichi I Nakayama

12

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1 September 2017

publication date

22 July 2008

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1 September 2017

number of pages

13

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based on heuristic

inferred from page(s)

published in

Human Molecular Genetics

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1 September 2017

volume

17

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1 September 2017

issue

20

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1 September 2017

page(s)

3191-3203

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The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

1 September 2017

cites work

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The kinesin-associated protein UNC-76 is required for axonal transport in the Drosophila nervous system

21 January 2018

1 reference

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Identification of a tissue-non-specific homologue of axonal fasciculation and elongation protein zeta-1

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Expression of fasciculation and elongation protein zeta-1 (FEZ1) in the developing rat brain

21 January 2018

1 reference

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Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Fasciculation and elongation protein zeta-1 (FEZ1) participates in the polarization of hippocampal neuron by controlling the mitochondrial motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region

21 January 2018

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Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth

21 January 2018

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Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

21 January 2018

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Disruption of two novel genes by a translocation co-segregating with schizophrenia

21 January 2018

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Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

21 January 2018

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How has DISC1 enabled drug discovery?

21 January 2018

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DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

21 January 2018

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Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

21 January 2018

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Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

21 January 2018

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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

21 January 2018

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The DISC locus in psychiatric illness

21 January 2018

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Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

21 January 2018

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Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs

21 January 2018

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Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development.

21 January 2018

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Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

21 January 2018

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Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts.

21 January 2018

1 reference

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Failure to confirm the association between the FEZ1 gene and schizophrenia in a Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

The FEZ1 gene shows no association to schizophrenia in Caucasian or African American populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Genetic animal models: focus on schizophrenia

21 January 2018

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Attention deficit/hyperactivity disorder: characteristics, interventions and models

21 January 2018

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Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

21 January 2018

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Modulatory functions of neurotransmitters in the striatum: ACh/dopamine/NMDA interactions

21 January 2018

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Overexpression of fasciculation and elongation protein zeta-1 (FEZ1) induces a post-entry block to retroviruses in cultured cells

21 January 2018

1 reference

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Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation.

21 January 2018

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Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

21 January 2018

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Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice.

21 January 2018

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Provocative tests with psychostimulant drugs in schizophrenia

21 January 2018

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Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Neural cell adhesion molecule-secreting transgenic mice display abnormalities in GABAergic interneurons and alterations in behavior.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Implications of normal brain development for the pathogenesis of schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Increased baseline occupancy of D2 receptors by dopamine in schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Pathophysiologically based treatment interventions in schizophrenia

21 January 2018

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A schizophrenia-related sensorimotor deficit links alpha 3-containing GABAA receptors to a dopamine hyperfunction

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Genes, dopamine and cortical signal-to-noise ratio in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Gap junctions among dendrites of cortical GABAergic neurons establish a dense and widespread intercolumnar network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

An inducer for glial cell line-derived neurotrophic factor and tumor necrosis factor-alpha protects against methamphetamine-induced rewarding effects and sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDN215

21 January 2018

Identifiers

DOI

10.1093/HMG/DDN215

1 reference

1 September 2017

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