Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity (Q38314973)

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scientific article published on March 2000

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English	Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity	scientific article published on March 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

author name string

Busse D

1

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2 September 2017

Doughty RS

2

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2 September 2017

Ramsey TT

3

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2 September 2017

Russell WE

4

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2 September 2017

Price JO

5

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2 September 2017

Flanagan WM

6

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2 September 2017

Shawver LK

7

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2 September 2017

Arteaga CL

8

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2 September 2017

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publication date

1 March 2000

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2 September 2017

number of pages

9

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Journal of Biological Chemistry

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2 September 2017

275

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2 September 2017

10

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2 September 2017

6987-6995

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PubMed publication ID

2 September 2017

SH2 and SH3 domains

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The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

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21 January 2018

Specificity within the EGF family/ErbB receptor family signaling network

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21 January 2018

Dimerization of cell surface receptors in signal transduction

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21 January 2018

Growth factors and cancer

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Type I receptor tyrosine kinases as targets for therapy in breast cancer

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21 January 2018

Signal transduction via the MAP kinases: proceed at your own RSK.

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21 January 2018

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway

1 reference

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21 January 2018

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

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21 January 2018

Inhibitors of mammalian G1 cyclin-dependent kinases

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21 January 2018

Mammalian G1 cyclins

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21 January 2018

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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21 January 2018

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

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21 January 2018

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

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21 January 2018

New insights into the tumor suppression function of P27(kip1)

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21 January 2018

Tyrosine kinase inhibition: an approach to drug development

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21 January 2018

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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21 January 2018

Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site.

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21 January 2018

Epidermal growth factor receptor gene-amplified MDA-468 breast cancer cell line and its nonamplified variants

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21 January 2018

A synthetic inhibitor of the mitogen-activated protein kinase cascade

1 reference

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21 January 2018

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1 reference

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21 January 2018

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1 reference

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21 January 2018

A cytosine analog that confers enhanced potency to antisense oligonucleotides

1 reference

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21 January 2018

Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells.

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21 January 2018

Endocytosis of growth factor receptors

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21 January 2018

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

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21 January 2018

Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein

1 reference

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21 January 2018

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

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21 January 2018

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

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21 January 2018

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

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21 January 2018

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

1 reference

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21 January 2018

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.10.6987

21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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21 January 2018

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

1 reference

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21 January 2018

Phosphoinositide kinases

1 reference

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21 January 2018

Downstream signalling events regulated by phosphatidylinositol 3-kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.10.6987

21 January 2018

Structural and functional diversity of phosphoinositide 3-kinases.

1 reference

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21 January 2018

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

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21 January 2018

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

1 reference

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Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

1 reference

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21 January 2018

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

1 reference

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21 January 2018

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

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21 January 2018

Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation

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21 January 2018

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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21 January 2018

Identifiers

10.1074/JBC.275.10.6987

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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