Development and Application of an LC-MS/MS Method for the Detection of the Vinyl Chloride-Induced DNA Adduct N2,3-Ethenoguanine in Tissues of Adult and Weanling Rats Following Exposure to [13C2]-VC (Q38430547)

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scientific article published on September 20, 2010

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English	Development and Application of an LC-MS/MS Method for the Detection of the Vinyl Chloride-Induced DNA Adduct N2,3-Ethenoguanine in Tissues of Adult and Weanling Rats Following Exposure to [13C2]-VC	scientific article published on September 20, 2010

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3 September 2017

Development and Application of an LC-MS/MS Method for the Detection of the Vinyl Chloride-Induced DNA Adduct N2,3-Ethenoguanine in Tissues of Adult and Weanling Rats Following Exposure to [13C2]-VC (English)

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10.1021/TX1001767

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2 July 2024

Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC (English)

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2 July 2024

3H-imidazo[2,1-b]purin-4(5H)-one

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ChEBI release 2020-05-28

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Esra Mutlu

1

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Europe PubMed Central

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3 September 2017

Darrell Winsett

6

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3 September 2017

Gary Hatch

7

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3 September 2017

Paul Evansky

8

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Europe PubMed Central

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3 September 2017

Leonard B. Collins

2

0000-0002-7734-9708

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Europe PubMed Central

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2 July 2024

Matthew D. Stout

3

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2 July 2024

Patricia B. Upton

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2 July 2024

Laura R. Daye

5

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2 July 2024

James A. Swenberg

9

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2 July 2024

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2 July 2024

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1 September 2010

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3 September 2017

20 September 2010

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2 July 2024

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2 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20799743/?tool=EBI

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2 July 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20799743/pdf/?tool=EBI

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2 July 2024

https://europepmc.org/articles/PMC3104734

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20799743

2 July 2024

https://europepmc.org/articles/PMC3104734?pdf=render

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2 July 2024

https://doi.org/10.1021/tx1001767

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2 July 2024

https://pubs.acs.org/doi/pdf/10.1021/tx1001767

1 reference

10.1021/TX1001767

https://api.crossref.org/works/10.1021/TX1001767

2 July 2024

Chemical Research in Toxicology

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

23

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

1485-1491

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

The use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

6 September 2017

Exocyclic DNA adducts as oxidative stress markers in colon carcinogenesis: potential role of lipid peroxidation, dietary fat and antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

6 September 2017

Vinyl chloride: still a cause for concern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

6 September 2017

Occupationally related angiosarcoma of the liver in the United Kingdom 1972-1994.

1 reference

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6 September 2017

Carcinogenicity bioassays of vinyl chloride monomer: a model of risk assessment on an experimental basis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

6 September 2017

Angiosarcoma of liver in the manufacture of polyvinyl chloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

6 September 2017

Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

6 September 2017

Molecular dosimetry and repair of N(2),3-ethenoguanine in rats exposed to vinyl chloride.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

14 September 2017

Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

14 September 2017

Vinyl chloride: an assessment of the risk of occupational exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

14 September 2017

Mutagenic and carcinogenic effects of vinyl chloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

14 September 2017

Induction of gene mutations and gene conversions by vinyl chloride metabolites in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

27 September 2017

Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Results of sputum, cytology among workers exposed to vinyl chloride monomer and to poly(vinyl chloride)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Angiosarcoma of the liver in a vinyl-chloride worker.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Induction of specific base-pair substitutions in E. coli trpA mutants by chloroethylene oxide, a carcinogenic vinyl chloride metabolite.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Metabolic activation of vinyl chloride, formation of nucleic acid adducts and relevance to carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

The vinyl chloride-derived nucleoside, N2,3-ethenoguanosine, is a highly efficient mutagen in transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Carcinogenicity of vinyl chloride in Sprague-Dawley rats after prenatal and postnatal exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Mutation induction in chinese hamster V79 cells by two vinyl chloride metabolites, chloroethylene oxide and 2-chloroacetaldehyde

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Evaluation of the genetic effects induced by vinyl chloride monomer (VCM) under mammalian metabolic activation: studies in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Metabolism of [14C]- and [36Cl]-labeled vinyl chloride in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

23 June 2018

Biodegradation of cis-1,2-dichloroethylene and vinyl chloride in anaerobic cultures enriched from landfill leachate sediment under Fe(III)-reducing conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

Fate of plasticised PVC products under landfill conditions: a laboratory-scale landfill simulation reactor study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

The effect of age and exposure duration on cancer induction by a known carcinogen in rats, mice, and hamsters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

Vinyl chloride-induced DNA adducts. I: Quantitative determination of N2,3-ethenoguanine based on electrophore labeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

Lifetime (149-week) oral carcinogenicity study of vinyl chloride in rats

1 reference

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31 August 2018

Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104734

31 August 2018

Quantitative analysis of the DNA adduct N2,3-ethenoguanine using liquid chromatography/electrospray ionization mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic activation of vinyl chloride by rat liver microsomes: low-dose kinetics and involvement of cytochrome P450 2E1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiosarcoma of the liver following vinyl chloride exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lifespan oral toxicity study of vinyl chloride in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of 7-(2-oxoethyl)guanine and N2,3-ethenoguanine in DNA hydrolysates by HPLC

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of the vinyl chloride oxidation products 1-chlorooxirane and 2-chloroacetaldehyde in the in vitro formation of etheno adducts of nucleic acid bases [corrected]

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoaffinity/gas chromatography/high-resolution mass spectrometry method for the detection of N(2),3-ethenoguanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of lipid peroxidation derived DNA damage in human colon carcinogenesis: studies on exocyclic base adducts as stable oxidative stress markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20799743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental Health Perspectives

6

41

85

author name string

Maltoni C.

publication date

1981

1 reference

10.1021/TX1001767

https://api.crossref.org/works/10.1021/TX1001767

2 July 2024

Cancer Research

21

37

253

author name string

Loprieno N.

publication date

1977

1 reference

10.1021/TX1001767

https://api.crossref.org/works/10.1021/TX1001767

2 July 2024

Cancer Research

39

62

5183

author name string

Morinello E. J.

publication date

2002

1 reference

10.1021/TX1001767

https://api.crossref.org/works/10.1021/TX1001767

2 July 2024

Cancer Research

40

62

5189

author name string

Morinello E. J.

publication date

2002

1 reference

10.1021/TX1001767

https://api.crossref.org/works/10.1021/TX1001767

2 July 2024

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10.1021/TX1001767

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Europe PubMed Central

PMC publication ID

3 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 September 2017

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