Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma. (Q38870822)

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15 February 2020

title

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma (English)

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Christine Pirker

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Bahil Ghanim

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Thomas Klikovits

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Michael Grusch

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Sabine Zöchbauer-Müller

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Gerwin Heller

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Walter Berger

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Balázs Döme

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Balázs Hegedűs

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Walter Klepetko

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author name string

Mir Alireza Hoda

2

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Tamas Garay

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Yawen W Dong

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Anita Rozsas

8

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Istvan Kenessey

9

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Ildiko Szirtes

10

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Marko Jakopovic

12

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Miroslav Samarzija

13

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Luka Brcic

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Izidor Kern

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Ales Rozman

16

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Helmut Popper

17

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Corinna Altenberger

20

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Barbara Ziegler

21

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publication date

14 July 2015

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15 February 2020

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volume

237

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issue

2

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page(s)

203-214

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Ecological association between asbestos-related diseases and historical asbestos consumption: an international analysis.

15 February 2020

cites work

1 reference

The epidemiology of mesothelioma

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Trimodality therapy with induction chemotherapy followed by extrapleural pneumonectomy and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma

21 January 2018

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Trimodality therapy for malignant pleural mesothelioma: results from an EORTC phase II multicentre trial.

21 January 2018

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ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells

21 January 2018

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H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis

21 January 2018

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Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma.

21 January 2018

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Integrin alpha 7 interacts with high temperature requirement A2 (HtrA2) to induce prostate cancer cell death

21 January 2018

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Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells

21 January 2018

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Cell migration or cytokinesis and proliferation?--revisiting the "go or grow" hypothesis in cancer cells in vitro.

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation

21 January 2018

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Ki67 index is an independent prognostic factor in epithelioid but not in non-epithelioid malignant pleural mesothelioma: a multicenter study

21 January 2018

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Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

21 January 2018

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Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

21 January 2018

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Genome-wide CpG island methylation analyses in non-small cell lung cancer patients.

21 January 2018

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Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers.

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Identification of genes that regulate epithelial cell migration using an siRNA screening approach

21 January 2018

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New roles of cyclin D1.

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Alpha7 integrin mediates cell adhesion and migration on specific laminin isoforms

21 January 2018

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The alpha7beta1 integrin mediates adhesion and migration of skeletal myoblasts on laminin

21 January 2018

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Quantitative analysis of integrin expression in effusions using flow cytometric immunophenotyping

21 January 2018

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Differential expression of the 67 kilodalton laminin receptor in epithelioid malignant mesothelioma and carcinomas that spread to serosal cavities.

21 January 2018

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Cytogenetic and molecular genetic changes in malignant mesothelioma.

21 January 2018

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High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas

21 January 2018

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Loss of the tumor suppressor gene NF2, encoding merlin, constitutively activates integrin-dependent mTORC1 signaling

21 January 2018

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The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

21 January 2018

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Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma

21 January 2018

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Identification of candidate oncogenes in human colorectal cancers with microsatellite instability

21 January 2018

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A review of transcriptome studies combined with data mining reveals novel potential markers of malignant pleural mesothelioma

21 January 2018

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Differential expression of extracellular matrix constituents and cell adhesion molecules between malignant pleural mesothelioma and mesothelial hyperplasia.

21 January 2018

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Cell growth inhibition and gene expression induced by the histone deacetylase inhibitor, trichostatin A, on human hepatoma cells

21 January 2018

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Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma.

21 January 2018

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Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome

21 January 2018

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Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors

21 January 2018

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Integrin α7 binds tissue inhibitor of metalloproteinase 3 to suppress growth of prostate cancer cells

21 January 2018

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Integrins: bidirectional, allosteric signaling machines

21 January 2018

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Integrin modulators: a patent review

21 January 2018

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Transcriptional activity of ATF3 in the stromal compartment of tumors promotes cancer progression.

21 January 2018

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Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

21 January 2018

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The α₂β₁ integrin is a metastasis suppressor in mouse models and human cancer

21 January 2018

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β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model

21 January 2018

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Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

21 January 2018

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Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.

21 January 2018

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Postmortem findings of malignant pleural mesothelioma: a two-center study of 318 patients.

21 January 2018

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Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4567

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26011651%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

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