Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs (Q38896015)

7 September 2017

Modeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs (English)

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7 September 2017

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spinal muscular atrophy

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inferred from title

neuromuscular junction

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10

Jun Takahashi

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7 September 2017

Michiko Yoshida

1

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7 September 2017

Shiho Kitaoka

2

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7 September 2017

Naohiro Egawa

3

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7 September 2017

Mayu Yamane

4

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7 September 2017

Ryunosuke Ikeda

5

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7 September 2017

Kayoko Tsukita

6

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7 September 2017

Naoki Amano

7

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7 September 2017

Akira Watanabe

8

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7 September 2017

Masafumi Morimoto

9

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7 September 2017

Hajime Hosoi

11

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7 September 2017

Tatsutoshi Nakahata

12

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7 September 2017

Haruhisa Inoue

13

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7 September 2017

Megumu K Saito

14

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7 September 2017

language of work or name

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19 March 2015

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7 September 2017

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7 September 2017

4

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7 September 2017

4

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7 September 2017

561-568

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Improved antisense oligonucleotide design to suppress aberrant SMN2 gene transcript processing: towards a treatment for spinal muscular atrophy

7 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Genetic correction of human induced pluripotent stem cells from patients with spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

A more efficient method to generate integration-free human iPS cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Characterization of human myoblast differentiation for tissue-engineering purposes by quantitative gene expression analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Impaired synaptic vesicle release and immaturity of neuromuscular junctions in spinal muscular atrophy mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Induced pluripotent stem cells from a spinal muscular atrophy patient

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Ramblings in the history of spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Identification and characterization of a spinal muscular atrophy-determining gene

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Valproic acid increases SMN2 expression and modulates SF2/ASF and hnRNPA1 expression in SMA fibroblast cell lines

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Drug screening for ALS using patient-specific induced pluripotent stem cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Synaptic defects in type I spinal muscular atrophy in human development

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Brief report: phenotypic rescue of induced pluripotent stem cell-derived motoneurons of a spinal muscular atrophy patient.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

The developmental pattern of myotubes in spinal muscular atrophy indicates prenatal delay of muscle maturation.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4400613

Neurofilament accumulation at the motor endplate and lack of axonal sprouting in a spinal muscular atrophy mouse model

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25801509

12 December 2020

inferred from PubMed ID database lookup

Motoneuron death in normal and spinal muscular atrophy-affected human fetuses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25801509

12 December 2020

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25801509

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.STEMCR.2015.02.010

1 reference

7 September 2017

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7 September 2017

PubMed publication ID

25801509

1 reference