The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. (Q38992060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24858040%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense (English)

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19 March 2020

5

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19 March 2020

author name string

Y Itahana

1

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19 March 2020

R Han

2

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19 March 2020

S Barbier

3

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19 March 2020

Z Lei

4

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19 March 2020

K Itahana

6

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19 March 2020

language of work or name

English

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publication date

26 May 2014

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19 March 2020

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19 March 2020

volume

34

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19 March 2020

issue

14

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19 March 2020

page(s)

1799-1810

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Blinded by the Light: The Growing Complexity of p53

19 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

Emerging roles of mitochondrial p53 and ARF.

21 January 2018

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Metabolic regulation by p53.

21 January 2018

1 reference

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Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

21 January 2018

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The contribution of endogenous sources of DNA damage to the multiple mutations in cancer

21 January 2018

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p53 regulation of metabolic pathways

21 January 2018

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A model for p53-induced apoptosis

21 January 2018

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Influence of induced reactive oxygen species in p53-mediated cell fate decisions.

21 January 2018

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

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Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD

21 January 2018

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

21 January 2018

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Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

21 January 2018

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The antioxidant function of the p53 tumor suppressor

21 January 2018

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Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking.

21 January 2018

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Temporal dissection of p53 function in vitro and in vivo

21 January 2018

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Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation

21 January 2018

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Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.

21 January 2018

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The p53MH algorithm and its application in detecting p53-responsive genes

21 January 2018

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21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

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Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9)

21 January 2018

1 reference

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Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

SLC2A9 is a high-capacity urate transporter in humans

21 January 2018

1 reference

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SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

21 January 2018

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Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

Mouse GLUT9: evidences for a urate uniporter.

21 January 2018

1 reference

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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

21 January 2018

1 reference

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Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS.

21 January 2018

1 reference

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

Loss of urate oxidase activity in hominoids and its evolutionary implications

21 January 2018

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Two independent mutational events in the loss of urate oxidase during hominoid evolution

21 January 2018

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Uric acid transport and disease

21 January 2018

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Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis

21 January 2018

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Decreased plasma antioxidants in patients with Alzheimer's disease.

21 January 2018

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Probenecid is a chemosensitizer in cancer cell lines

21 January 2018

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Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

21 January 2018

Oxidative Decay of DNA

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https://api.crossref.org/works/10.1038%2FONC.2014.119

Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

Mitochondrial p32 is a critical mediator of ARF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.119

Mdm2 RING mutation enhances p53 transcriptional activity and p53-p300 interaction

21 January 2018

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Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil

21 January 2018

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Serum uric acid levels and the risk of Parkinson disease

21 January 2018

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Delayed ageing through damage protection by the Arf/p53 pathway

21 January 2018

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21 January 2018

Antioxidants and aging

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Salivary uric acid at the acidic pH of the stomach is the principal defense against nitrite-derived reactive species: Sparing effects of chlorogenic acid and serum albumin

31 March 2020

1 reference

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The protein family of glucose transport facilitators: It's not only about glucose after all.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24858040

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24858040

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24858040%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

19 March 2020

1041413348

0 references

1 reference

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