Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens. (Q39170177)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23563200%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens (English)

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28 February 2020

main subject

cell line

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Merkel cell carcinoma

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1

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28 February 2020

Jochen Utikal

5

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28 February 2020

author name string

Christina Dreher

2

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28 February 2020

Sabrina Angermeyer

3

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28 February 2020

Andreas Borst

4

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28 February 2020

Sebastian Haferkamp

6

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28 February 2020

Wiebke K Peitsch

7

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28 February 2020

David Schrama

8

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28 February 2020

Sonja Hesbacher

9

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28 February 2020

language of work or name

English

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publication date

5 April 2013

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Journal of Investigative Dermatology

28 February 2020

published in

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28 February 2020

volume

133

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28 February 2020

issue

10

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28 February 2020

page(s)

2453-2460

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describes a project that uses

28 February 2020

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Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

1 reference

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Merkel cell carcinoma

1 reference

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Loss of function and p53 protein stabilization

1 reference

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Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens

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Clonal integration of a polyomavirus in human Merkel cell carcinoma

1 reference

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Update on human polyomaviruses and cancer

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pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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p53 and metabolism: Inside the TIGAR.

1 reference

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The p53 pathway: positive and negative feedback loops

1 reference

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Merkel cell carcinoma: changing incidence trends

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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Merkel cell carcinoma and Merkel cell polyomavirus: evidence for hit-and-run oncogenesis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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Activation of the MAP kinase pathway induces apoptosis in the Merkel cell carcinoma cell line UISO.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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p14ARF Hypermethylation Is Common but INK4a-ARF Locus or p53 Mutations Are Rare in Merkel Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

The complexity of p53 stabilization and activation

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Merkel cell carcinoma: more deaths but still no pathway to blame

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

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Characterisation of four Merkel cell carcinoma adherent cell lines

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https://api.crossref.org/works/10.1038%2FJID.2013.169

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The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

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https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

The p53-Mdm2 module and the ubiquitin system.

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https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis

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https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3

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https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Cisplatin-based chemotherapy for merkel cell carcinoma of the skin

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Role of T antigen interactions with p53 in tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

High-risk Merkel cell carcinoma of the skin treated with synchronous carboplatin/etoposide and radiation: a Trans-Tasman Radiation Oncology Group Study--TROG 96:07.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Does chemotherapy improve survival in high-risk stage I and II Merkel cell carcinoma of the skin?

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https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Merkel cell carcinoma: in vitro and in vivo characteristics of a new cell line.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Simian virus 40 T antigen can regulate p53-mediated transcription independent of binding p53.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2013.169

7 January 2021

Merkel cell carcinoma of the skin: pathological and molecular evidence for a causative role of MCV in oncogenesis

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https://api.crossref.org/works/10.1038%2FJID.2013.169

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Recent advances in the therapeutic perspectives of Nutlin-3.

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Divorcing ARF and p53: an unsettled case

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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

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Merkel cell polyomavirus infection, large T antigen, retinoblastoma protein and outcome in Merkel cell carcinoma.

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Gain of function of p53 cancer mutants in disrupting critical DNA damage response pathways

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p53 alterations in human cancer: more questions than answers.

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Chemotherapy in neuroendocrine/Merkel cell carcinoma of the skin: case series and review of 204 cases

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Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

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Contrasting effects of nutlin-3 on TRAIL- and docetaxel-induced apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells

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Mutation analysis of P73 and TP53 in Merkel cell carcinoma

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Combined karyotyping, CGH and M-FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma

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Chemotherapy for patients with locally advanced or metastatic Merkel cell carcinoma.

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Live or let die: the cell's response to p53

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p53 and its family members -- reporter genes may not see the difference

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Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas

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