Catalytic promiscuity and heme-dependent redox regulation of H2S synthesis (Q39173063)

17 June 2018

title

Catalytic promiscuity and heme-dependent redox regulation of H2S synthesis (English)

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17 June 2018

author name string

Ruma Banerjee

series ordinal

1

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17 June 2018

publication date

7 March 2017

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17 June 2018

Current Opinion in Chemical Biology

published in

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17 June 2018

volume

37

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17 June 2018

page(s)

115-121

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17 June 2018

Thioethers as markers of hydrogen sulfide production in homocystinurias.

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Heme regulation of human cystathionine beta-synthase activity: insights from fluorescence and Raman spectroscopy

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Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions

22 June 2018

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H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia

22 June 2018

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Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation

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Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase

22 June 2018

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Thioredoxin-dependent enzymatic activation of mercaptopyruvate sulfurtransferase. An intersubunit disulfide bond serves as a redox switch for activation

22 June 2018

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22 June 2018

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S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme

22 June 2018

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Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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The structure of a domain common to archaebacteria and the homocystinuria disease protein

22 June 2018

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22 June 2018

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22 June 2018

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Purification and characterization of cysteine aminotransferase from rat liver cytosol

22 June 2018

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Homolanthionine excretion in homocystinuria

22 June 2018

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Enzyme recruitment in evolution of new function

22 June 2018

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Purification and characterization of mitochondrial cysteine aminotransferase from rat liver

22 June 2018

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Heme-dependent Metabolite Switching Regulates H2S Synthesis in Response to Endoplasmic Reticulum (ER) Stress.

22 June 2018

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A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells

21 August 2018

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Dioxygen reactivity and heme redox potential of truncated human cystathionine beta-synthase

21 August 2018

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21 August 2018

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Mercuric chloride-induced spin or ligation state changes in ferric or ferrous human cystathionine beta-synthase inhibit enzyme activity

21 August 2018

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Characterization of NO binding to human cystathionine beta-synthase: possible implications of the effects of CO and NO binding to the human enzyme

21 August 2018

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Pyridoxal phosphate binding sites are similar in human heme-dependent and yeast heme-independent cystathionine beta-synthases. Evidence from 31P NMR and pulsed EPR spectroscopy that heme and PLP cofactors are not proximal in the human enzyme

21 August 2018

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Enzymatic desulfuration of beta-mercaptopyruvate to pyruvate

21 August 2018

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12 December 2020

Cysteine sulfinate aminotransferase and aspartate aminotransferase isoenzymes of rat brain. Purification, characterization, and further evidence for identity

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12 December 2020

Beta mercaptolactate-cysteine disulfide: analog of cystine in the urine of a mentally retarded patient

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12 December 2020

Inhibitory effect of mercaptoethanol and hypotaurine on the desulfhydration of cysteine by cystathionase

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12 December 2020

Hepatocyte-catalysed detoxification of cyanide by L- and D-cysteine

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12 December 2020

Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites

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12 December 2020

Underground metabolism

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12 December 2020

10.1016/J.CBPA.2017.02.021

Identifiers

DOI

1 reference

17 June 2018

PMC publication ID

5410396

1 reference

17 June 2018

PubMed publication ID

28282633

1 reference

17 June 2018