Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation (Q39262788)

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English	Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation (English)

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

0 references

apoptotic process

0 references

author name string

Weiyang He

1

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Qiong Wang

2

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Jennings Xu

3

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Xiuling Xu

4

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Mabel T Padilla

5

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Guosheng Ren

6

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Xin Gou

7

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

Yong Lin

8

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

publication date

10 October 2012

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

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Europe PubMed Central

PMC publication ID

10 September 2017

8

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

12

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Europe PubMed Central

PMC publication ID

10 September 2017

1811-1821

1 reference

Europe PubMed Central

PMC publication ID

10 September 2017

TRAIL signaling and synergy mechanisms used in TRAIL-based combination therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Autophagy: renovation of cells and tissues

1 reference

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10 September 2017

The autophagic paradox in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Autophagy as a mediator of chemotherapy-induced cell death in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

JNK regulates FoxO-dependent autophagy in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

TRAIL receptor signaling and therapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

1 reference

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10 September 2017

Methods in mammalian autophagy research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

TRAIL receptor targeting therapies for non-small cell lung cancer: current status and perspectives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Autophagy: principles and significance in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Tumor therapeutics by design: targeting and activation of death receptors

1 reference

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10 September 2017

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

TRAIL and NFkappaB signaling--a complex relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

The true face of JNK activation in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

The expanding role of mitochondria in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

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Modulation of cell death by Bcl-XL through caspase interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

10 September 2017

Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis

1 reference

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14 September 2017

Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

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IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells

1 reference

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14 September 2017

Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

14 September 2017

Enhancement of tumor-TRAIL susceptibility by modulation of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3541290

14 September 2017

Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance. Involvement of Bcl-xL.

1 reference

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14 September 2017

Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3.

1 reference

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14 September 2017

Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors

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Oxaliplatin uses JNK to restore TRAIL sensitivity in cancer cells through Bcl-xL inactivation.

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21 August 2018

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

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12 December 2020

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10.4161/AUTO.22145

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Europe PubMed Central

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10 September 2017

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10 September 2017

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10 September 2017

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