Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression. (Q39337368)

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3 February 2020

title

Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression (English)

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3 February 2020

3

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Mike Baldwin

5

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author name string

T D Nguyen

1

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3 February 2020

S Markova

2

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J M Gow

4

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M Habashian

6

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M V Relling

7

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M J Ratain

8

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D L Kroetz

9

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publication date

5 June 2012

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The Pharmacogenomics Journal

3 February 2020

published in

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volume

13

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issue

5

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page(s)

396-402

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Association of ABCC2 polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients

3 February 2020

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ABCC2/Abcc2: a multispecific transporter with dominant excretory functions.

11 September 2017

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Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein

11 September 2017

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11 September 2017

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Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene

11 September 2017

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11 September 2017

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Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

11 September 2017

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cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

11 September 2017

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Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function.

11 September 2017

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MRP2 haplotypes confer differential susceptibility to toxic liver injury

14 September 2017

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Role of MRP2 and GSH in intrahepatic cycling of toxins

14 September 2017

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Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

25 September 2017

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The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man.

17 June 2018

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Association of the c.3972C>T variant of the multidrug resistance-associated protein 2 Gene (MRP2/ABCC2) with susceptibility to bile duct cancer

17 June 2018

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Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.

21 August 2018

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Interaction of hepatocyte nuclear factors in transcriptional regulation of tissue specific hormonal expression of human multidrug resistance-associated protein 2 (abcc2).

21 August 2018

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Association of ATP-binding cassette, sub-family C, number 2 (ABCC2) genotype with pharmacokinetics of irinotecan in Japanese patients with metastatic colorectal cancer treated with irinotecan plus infusional 5-fluorouracil/leucovorin (FOLFIRI).

21 August 2018

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Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.

21 August 2018

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Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol

21 August 2018

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Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients

21 August 2018

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Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer.

21 August 2018

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Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes.

21 August 2018

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Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.

21 August 2018

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Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.

21 August 2018

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21 August 2018

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21 August 2018

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NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity

21 August 2018

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MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas.

21 August 2018

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Lack of association between ABCC2 gene variants and treatment response in epilepsy

21 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FTPJ.2012.20

Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects

21 January 2018

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12 December 2020

Role for drug transporters beyond tumor resistance: hepatic functional imaging and genotyping of multidrug resistance transporters for the prediction of irinotecan toxicity

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12 December 2020

Multidrug resistance protein 2 genetic polymorphisms influence mycophenolic acid exposure in renal allograft recipients

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12 December 2020

Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping

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12 December 2020

Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex

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12 December 2020

Identifiers

DOI

10.1038/TPJ.2012.20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22664480%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

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3 February 2020

PubMed publication ID

22664480

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22664480%20AND%20SRC:MED&resulttype=core&format=json