A functional network of the tumor suppressors APC, hDlg, and PTEN, that relies on recognition of specific PDZ-domains. (Q39376108)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434720%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

A functional network of the tumor suppressors APC, hDlg, and PTEN, that relies on recognition of specific PDZ-domains (English)

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26 January 2020

4

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26 January 2020

author name string

Natalia S Sotelo

series ordinal

1

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26 January 2020

Miguel Valiente

series ordinal

2

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26 January 2020

Anabel Gil

series ordinal

3

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26 January 2020

publication date

1 August 2012

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Journal of Cellular Biochemistry

26 January 2020

published in

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26 January 2020

volume

113

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26 January 2020

issue

8

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26 January 2020

page(s)

2661-2670

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E6 and E7 from human papillomavirus type 16 cooperate to target the PDZ protein Na/H exchange regulatory factor 1.

26 January 2020

cites work

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Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene

21 January 2018

1 reference

Haplo-insufficiency: a driving force in cancer

21 January 2018

1 reference

NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN.

21 January 2018

1 reference

APC shuttling to the membrane, nucleus and beyond

21 January 2018

1 reference

Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy

21 January 2018

1 reference

Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97.

21 January 2018

1 reference

NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer

21 January 2018

1 reference

Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ

21 January 2018

1 reference

Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

21 January 2018

1 reference

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

21 January 2018

1 reference

Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

21 January 2018

1 reference

Characterization of PDZ-binding kinase, a mitotic kinase

21 January 2018

1 reference

PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control

21 January 2018

1 reference

Regulation of the PTEN phosphatase

21 January 2018

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PTEN acetylation modulates its interaction with PDZ domain

21 January 2018

1 reference

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

1 reference

Cell polarity proteins: common targets for tumorigenic human viruses

21 January 2018

1 reference

PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression

21 January 2018

1 reference

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

A systematic analysis of human papillomavirus (HPV) E6 PDZ substrates identifies MAGI-1 as a major target of HPV type 16 (HPV-16) and HPV-18 whose loss accompanies disruption of tight junctions

21 January 2018

1 reference

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

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SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit

21 January 2018

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Indirect mechanisms of carcinogenesis via downregulation of PTEN function.

21 January 2018

1 reference

Identification of mitogen-activated protein/extracellular signal-responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc-large

21 January 2018

1 reference

Modular organization of the PDZ domains in the human discs-large protein suggests a mechanism for coupling PDZ domain-binding proteins to ATP and the membrane cytoskeleton

21 January 2018

1 reference

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

21 January 2018

1 reference

Adenomatous polyposis coli (APC) protein regulates epithelial cell migration and morphogenesis via PDZ domain-based interactions with plasma membranes

21 January 2018

1 reference

PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma

21 January 2018

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Differential up-regulation of MAP kinase phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun converge in the control of the growth arrest versus proliferation response of MCF-7 breast cancer cells to phorbol ester

21 January 2018

1 reference

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

21 January 2018

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New perspectives on APC control of cell fate and proliferation in colorectal cancer

21 January 2018

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Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for apical membrane morphogenesis in photoreceptor epithelial cells

21 January 2018

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p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

21 January 2018

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Tenets of PTEN tumor suppression

21 January 2018

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PDZ domains: the building blocks regulating tumorigenesis

21 January 2018

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Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

21 January 2018

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PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling

21 January 2018

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Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

21 January 2018

1 reference

Structural characterization of the intermolecular interactions of synapse-associated protein-97 with the NR2B subunit of N-methyl-D-aspartate receptors

21 January 2018

1 reference

Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

21 January 2018

1 reference

Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

21 January 2018

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Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

21 January 2018

1 reference

Structures of a human papillomavirus (HPV) E6 polypeptide bound to MAGUK proteins: mechanisms of targeting tumor suppressors by a high-risk HPV oncoprotein

21 January 2018

1 reference

Molecular Basis for the Recognition of Adenomatous Polyposis Coli by the Discs Large 1 Protein

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCB.24141

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434720%20AND%20SRC:MED&resulttype=core&format=json

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26 January 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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