ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance. (Q39408275)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266654%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance (English)

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20 January 2020

3

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20 January 2020

author name string

Megan McKerlie

series ordinal

1

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20 January 2020

Sichun Lin

series ordinal

2

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20 January 2020

language of work or name

English

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publication date

20 January 2012

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20 January 2020

published in

Nucleic Acids Research

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20 January 2020

volume

40

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20 January 2020

issue

9

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20 January 2020

page(s)

3975-3989

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Creative Commons Attribution-NonCommercial 3.0 Unported

20 January 2020

copyright license

start time

4 October 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3351164/fullTextXML

inferred from PubMed Central ID database lookup

cites work

TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres

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Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

11 September 2017

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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

11 September 2017

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Human XPF controls TRF2 and telomere length maintenance through distinctive mechanisms

11 September 2017

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How shelterin protects mammalian telomeres

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MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

11 September 2017

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XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening

11 September 2017

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Functional human telomeres are recognized as DNA damage in G2 of the cell cycle

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Shelterin: the protein complex that shapes and safeguards human telomeres

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DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

11 September 2017

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

11 September 2017

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Homologous recombination generates T-loop-sized deletions at human telomeres

11 September 2017

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Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

11 September 2017

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TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex

11 September 2017

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ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

11 September 2017

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Rap1 affects the length and heterogeneity of human telomeres

11 September 2017

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DNA damage foci at dysfunctional telomeres

11 September 2017

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Intracellular localization of proteasomes

11 September 2017

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Proteasome-dependent processing of nuclear proteins is correlated with their subnuclear localization

11 September 2017

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Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2

11 September 2017

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Senescence Induced by Altered Telomere State, Not Telomere Loss

11 September 2017

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ATM function and telomere stability

11 September 2017

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Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

11 September 2017

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Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

11 September 2017

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Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

11 September 2017

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11 September 2017

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11 September 2017

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TRF2 Protects Human Telomeres from End-to-End Fusions

11 September 2017

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11 September 2017

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Control of telomere length by the human telomeric protein TRF1

11 September 2017

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11 September 2017

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

11 September 2017

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11 September 2017

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11 September 2017

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Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

14 September 2017

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Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation

14 September 2017

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Recombinant ATM protein complements the cellular A-T phenotype

14 September 2017

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Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

25 September 2017

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Cyclin B-dependent kinase 1 regulates human TRF1 to modulate the resolution of sister telomeres.

25 September 2017

1 reference

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Plk1 phosphorylation of TRF1 is essential for its binding to telomeres

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351164

Importance of TRF1 for Functional Telomere Structure

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351164

Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3351164

Accelerated telomere shortening in ataxia telangiectasia

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKS035

Telomeric structure in cells with chromosome end associations

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKS035

Influence of ATM function on telomere metabolism

21 January 2018

1 reference

12 December 2020

Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasia

1 reference

12 December 2020

Proteasomes degrade proteins in focal subdomains of the human cell nucleus

1 reference

12 December 2020

The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKS035

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266654%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266654%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

22266654

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22266654%20AND%20SRC:MED&resulttype=core&format=json