MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells. (Q39490299)

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10 February 2020

title

MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells (English)

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10 February 2020

3

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10 February 2020

Agnese Mariotti

8

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10 February 2020

author name string

C Carrascosa

1

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10 February 2020

R G Obula

2

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10 February 2020

H-A Lehr

4

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10 February 2020

M Delorenzi

5

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10 February 2020

M Frattini

6

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C Rüegg

7

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10 February 2020

language of work or name

English

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publication date

15 August 2011

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10 February 2020

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10 February 2020

volume

31

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10 February 2020

issue

12

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10 February 2020

page(s)

1521-1532

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Bovine PAS-6/7 binds alpha v beta 5 integrins and anionic phospholipids through two domains

10 February 2020

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Mfge8 is critical for mammary gland remodeling during involution

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Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer

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Circulating human mammary epithelial antigens in breast cancer

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Surface differentiation antigens of human mammary epithelial cells carried on the human milk fat globule

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Cadherins and catenins in breast cancer

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The EGF repeat and discoidin domain protein, SED1/MFG-E8, is required for mammary gland branching morphogenesis

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Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8

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Identification of a factor that links apoptotic cells to phagocytes

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Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

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Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis

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Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

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Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

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Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms

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Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase

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Regulators of G1 cyclin-dependent kinases and cancers

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Estrogen-Induced Ets-1 Promotes Capillary Formation in an in vitro Tumor Angiogenesis Model

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Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

21 January 2018

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TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

21 January 2018

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Lactation-dependent expression of an mRNA splice variant with an exon for a multiply O-glycosylated domain of mouse milk fat globule glycoprotein MFG-E8.

21 January 2018

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Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer

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Biochemical and histological characterization of antigens preferentially expressed on the surface and cytoplasm of breast carcinoma cells identified by monoclonal antibodies against the human milk fat globule

21 January 2018

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SED1/MFG-E8: a bi-motif protein that orchestrates diverse cellular interactions

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Cyclin D1 and breast cancer

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Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer

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Lactadherin promotes VEGF-dependent neovascularization

21 January 2018

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The effect of unlocking RGD-motifs in collagen I on pre-osteoblast adhesion and differentiation

21 January 2018

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Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion

21 January 2018

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Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

21 January 2018

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The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers

21 January 2018

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Specific protection against breast cancers by cyclin D1 ablation

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MFG-E8/Lactadherin Promotes Tumor Growth in an Angiogenesis-Dependent Transgenic Mouse Model of Multistage Carcinogenesis

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Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment

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A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor

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