Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and -resistant human ovarian cancer cells (Q39786842)

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scientific article published on 16 October 2009

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English	Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and -resistant human ovarian cancer cells	scientific article published on 16 October 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and -resistant human ovarian cancer cells (English)

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Europe PubMed Central

PubMed publication ID

14 September 2017

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inferred from title

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Gaetano Marverti

1

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14 September 2017

author name string

Alessio Ligabue

2

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14 September 2017

Monica Montanari

3

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14 September 2017

Davide Guerrieri

4

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14 September 2017

Matteo Cusumano

5

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14 September 2017

Maria Letizia Di Pietro

6

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14 September 2017

Leonarda Troiano

7

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14 September 2017

Elena Di Vono

8

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14 September 2017

Stefano Iotti

9

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14 September 2017

Giovanna Farruggia

10

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14 September 2017

Federica Wolf

11

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14 September 2017

Maria Giuseppina Monti

12

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14 September 2017

Chiara Frassineti

13

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14 September 2017

publication date

16 October 2009

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14 September 2017

Investigational New Drugs

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14 September 2017

29

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14 September 2017

1

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14 September 2017

73-86

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PubMed publication ID

14 September 2017

Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

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Comparison of the mutagenic and clastogenic activity of amsacrine and other DNA-intercalating drugs in cultured V79 Chinese hamster cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

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A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

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Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors

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https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

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Quantification of cells cultured on 96-well plates

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https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

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The intercalation to DNA of bipyridyl complexes of platinum(II) with thioureas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

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Genotoxic effects of chemicals in the single cell gel (SCG) test with human blood cells in relation to the induction of sister-chromatid exchanges (SCE)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

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Expression of Bax and Bcl-2 proteins during hypoxia in cerebral cortical neuronal nuclei of newborn piglets: effect of administration of magnesium sulfate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human DNA topoisomerase II by hydroquinone and p-benzoquinone, reactive metabolites of benzene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships of anthracyclines relative to effects on macromolecular syntheses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naphthalimides as anti-cancer agents: synthesis and biological activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atherosclerosis and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnesium and the control of cell proliferation: looking for a needle in a haystack.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An osmotic model for the fusion of biological membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible involvement of thioredoxin reductase as well as thioredoxin in cellular sensitivity to cis-diamminedichloroplatinum (II).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

8-hydroxyquinoline derivatives as fluorescent sensors for magnesium in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Hsp90 acts synergistically with topoisomerase II poisons to increase the apoptotic killing of cells due to an increase in topoisomerase II mediated DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cisplatin-resistant murine leukemia cell line exhibits increased topoisomerase II activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance due to impaired DNA cleavage in a VP-16-resistant human leukemia cell line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Membrane Potential and DNA Stainability in Human Sperm Cells: A Flow Cytometry Analysis with Implications for Male Infertility

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA topoisomerase II alpha expression is associated with alkylating agent resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemically-induced and Thermally-induced Cell Fusion: Lipid-Lipid Interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous detection of chromosomal aberrations and sister-chromatid exchanges: experience with DNA intercalating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of cis-diamminedichloroplatinum (II) accumulation and cytotoxicity by spermine in sensitive and resistant human ovarian carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of extracellular magnesium on topoisomerase II activity and expression in human leukemia HL-60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial defects in cis-diamminedichloroplatinum(II)-resistant human ovarian carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiparametric analysis of cells with different mitochondrial membrane potential during apoptosis by polychromatic flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria are intracellular magnesium stores: investigation by simultaneous fluorescent imagings in PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the anti-proliferative effects of novel DNA-intercalating bipyridyl-thiourea-Pt(II) complexes against cisplatin-sensitive and -resistant human ovarian cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of resistance to cisplatin and carboplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19834646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-009-9336-3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

release_i2zsdxg2cbbobnabceupumc35q

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

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