Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain (Q39854967)

15 September 2017

title

Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain (English)

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15 September 2017

3

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15 September 2017

Mareike Wittenbrink

1

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15 September 2017

Jessica Spreu

series ordinal

2

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15 September 2017

language of work or name

English

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publication date

1 June 2009

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European Journal of Immunology

15 September 2017

published in

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15 September 2017

volume

39

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15 September 2017

issue

6

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15 September 2017

page(s)

1642-1651

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UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells

15 September 2017

cites work

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Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D

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Letal, A tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells

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Structural studies of allelic diversity of the MHC class I homolog MIC-B, a stress-inducible ligand for the activating immunoreceptor NKG2D

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Human Cytomegalovirus-Encoded UL16 Discriminates MIC Molecules by Their 2 Domains

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Promiscuity and the single receptor: NKG2D.

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7 January 2021

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

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7 January 2021

ULBP4 is a novel ligand for human NKG2D

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7 January 2021

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3

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7 January 2021

Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family

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7 January 2021

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

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7 January 2021

An activating immunoreceptor complex formed by NKG2D and DAP10

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7 January 2021

The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure.

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7 January 2021

Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

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7 January 2021

NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells

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7 January 2021

Tumor cell recognition by the NK cell activating receptor NKG2D.

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7 January 2021

NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy

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7 January 2021

Viral inhibitors of NKG2D ligands: friends or foes of immune surveillance?

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7 January 2021

Evolutionary struggles between NK cells and viruses

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7 January 2021

NKG2D ligands in tumor immunity

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7 January 2021

Symmetry Recognizing Asymmetry

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7 January 2021

MIC and other NKG2D ligands: from none to too many.

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7 January 2021

Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity

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7 January 2021

Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein

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7 January 2021

Down-regulation of the NKG2D ligand MICA by the human cytomegalovirus glycoprotein UL142

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7 January 2021

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium

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7 January 2021

Diversification, expression, and gamma delta T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules

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7 January 2021

Immune evasion of natural killer cells by viruses

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7 January 2021

RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200839074

7 January 2021

Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200839074

7 January 2021

Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D

1 reference

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7 January 2021

Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3

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7 January 2021

Identifiers

DOI

10.1002/EJI.200839074

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15 September 2017

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