The Src tyrosine kinase Hck is required for Tel-Abl- but not for Tel-Jak2-induced cell transformation. (Q40235633)

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29 December 2019

title

The Src tyrosine kinase Hck is required for Tel-Abl- but not for Tel-Jak2-induced cell transformation (English)

1 reference

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Virginie Penard-Lacronique

29 December 2019

author

3

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29 December 2019

author name string

Pecquet C

1

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29 December 2019

Nyga R

2

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29 December 2019

Smithgall TE

4

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29 December 2019

Murakami H

5

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29 December 2019

Régnier A

6

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29 December 2019

Lassoued K

7

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29 December 2019

Gouilleux F

8

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29 December 2019

language of work or name

English

0 references

publication date

4 September 2006

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29 December 2019

1 reference

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29 December 2019

volume

26

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29 December 2019

issue

11

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29 December 2019

page(s)

1577-1585

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SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

29 December 2019

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The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, Hck

21 January 2018

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A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2.

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BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

21 January 2018

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

21 January 2018

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Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

21 January 2018

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

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Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

21 January 2018

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Chronic myelocytic leukemia with eosinophilia, t(9;12)(q34;p13), and ETV6-ABL gene rearrangement: case report and review of the literature

21 January 2018

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The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.

21 January 2018

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A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

21 January 2018

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Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12).

21 January 2018

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

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Transformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective Hck

21 January 2018

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Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

21 January 2018

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Activation of the NF-kappaB pathway by the leukemogenic TEL-Jak2 and TEL-Abl fusion proteins leads to the accumulation of antiapoptotic IAP proteins and involves IKKalpha.

21 January 2018

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The Tel-Abl (ETV6-Abl) tyrosine kinase, product of complex (9;12) translocations in human leukemia, induces distinct myeloproliferative disease in mice

21 January 2018

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A direct binding site for Grb2 contributes to transformation and leukemogenesis by the Tel-Abl (ETV6-Abl) tyrosine kinase

21 January 2018

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Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase

21 January 2018

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Cooperation between STAT5 and phosphatidylinositol 3-kinase in the IL-3-dependent survival of a bone marrow derived cell line

21 January 2018

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Involvement of the NF-kappaB pathway in the transforming properties of the TEL-Jak2 leukemogenic fusion protein

21 January 2018

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

21 January 2018

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Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

21 January 2018

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Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells

21 January 2018

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The interaction of the Bcr-Abl tyrosine kinase with the Src kinase Hck is mediated by multiple binding domains

21 January 2018

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Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

21 January 2018

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The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases

21 January 2018

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The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways.

21 January 2018

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The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr

21 January 2018

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Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate-resistant Bcr-Abl kinases

21 January 2018

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Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

21 January 2018

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A transgenic mouse model for TEL-JAK2-induced B-cell lymphoma/leukemia

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1209949

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16953222%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

1032244112

0 references

1 reference