Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR. (Q40478910)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15610065%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR (English)

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6 January 2020

3

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6 January 2020

Lars C Pedersen

4

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6 January 2020

author name string

Akiko Ueda

1

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6 January 2020

Kenji Matsui

2

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6 January 2020

Tatsuya Sueyoshi

5

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6 January 2020

Masahiko Negishi

6

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6 January 2020

language of work or name

English

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publication date

1 June 2005

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6 January 2020

number of pages

8

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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6 January 2020

volume

388

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6 January 2020

issue

Pt 2

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6 January 2020

page(s)

623-630

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Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

6 January 2020

cites work

1 reference

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Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

22 September 2017

1 reference

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The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

22 September 2017

1 reference

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Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

22 September 2017

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Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

22 September 2017

1 reference

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The coregulator exchange in transcriptional functions of nuclear receptors

22 September 2017

1 reference

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Orphan nuclear receptors: from gene to function

22 September 2017

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

22 September 2017

1 reference

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The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

22 September 2017

1 reference

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The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

22 September 2017

1 reference

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Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

22 September 2017

1 reference

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

22 September 2017

1 reference

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138970

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

22 September 2017

1 reference

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

22 September 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

22 September 2017

1 reference

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

22 September 2017

1 reference

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The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module

25 September 2017

1 reference

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Selective LXXLL peptides antagonize transcriptional activation by the retinoid-related orphan receptor RORgamma

25 September 2017

1 reference

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Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene

17 June 2018

1 reference

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The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction

17 June 2018

1 reference

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The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity.

20 August 2018

1 reference

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Residue threonine 350 confers steroid hormone responsiveness to the mouse nuclear orphan receptor CAR.

20 August 2018

1 reference

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The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

20 August 2018

1 reference

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20 August 2018

Identifiers

DOI

10.1042/BJ20041572

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15610065%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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6 January 2020

PubMed publication ID

15610065

1 reference