Metabolic modeling of muscle metabolism identifies key reactions linked to insulin resistance phenotypes (Q41300995)

29 September 2017

Metabolic modeling of muscle metabolism identifies key reactions linked to insulin resistance phenotypes (English)

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29 September 2017

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Christopher Nogiec

1

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29 September 2017

Alison Burkart

2

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29 September 2017

Jonathan M Dreyfuss

3

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29 September 2017

Carles Lerin

4

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29 September 2017

Simon Kasif

5

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29 September 2017

Mary-Elizabeth Patti

6

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29 September 2017

2 January 2015

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29 September 2017

13

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inferred from page(s)

published in

Molecular Metabolism

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29 September 2017

4

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29 September 2017

3

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29 September 2017

151-163

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describes a project that uses

29 September 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/4338313

inferred from PubMed Central ID database lookup

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Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients

1 October 2017

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1 October 2017

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1 October 2017

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Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

1 October 2017

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Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone

1 October 2017

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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

1 October 2017

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The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

1 October 2017

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1 October 2017

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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

19 August 2018

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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

1 October 2017

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1 October 2017

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Fatty acid oxidation disorders

1 October 2017

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Bcl-2-dependent oxidation of pyruvate dehydrogenase-E2, a primary biliary cirrhosis autoantigen, during apoptosis

1 October 2017

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Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints

1 October 2017

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Fuel selection in human skeletal muscle in insulin resistance: a reexamination

1 October 2017

1 reference

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Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex

1 October 2017

1 reference

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Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

1 October 2017

1 reference

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Computational reconstruction of tissue‐specific metabolic models: application to human liver metabolism

1 October 2017

1 reference

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Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

17 June 2018

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Paradoxical Associations of Insulin Resistance With Total and Cardiovascular Mortality in Humans.

17 June 2018

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19 August 2018

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Thiamine ameliorates diabetes-induced inhibition of pyruvate dehydrogenase (PDH) in rat heart mitochondria: investigating the discrepancy between PDH activity and PDH E1alpha phosphorylation in cardiac fibroblasts exposed to high glucose

19 August 2018

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Candidate metabolic network states in human mitochondria. Impact of diabetes, ischemia, and diet.

19 August 2018

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PDH kinase inhibitors: a novel therapy for Type II diabetes?

19 August 2018

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12 December 2020

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

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12 December 2020

Derangements of pyruvate dehydrogenase in circulating lymphocytes of NIDDM patients and their healthy offspring

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12 December 2020

Network-based prediction of human tissue-specific metabolism

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12 December 2020

Human erythrocyte and plasma amino acid concentrations during exercise

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12 December 2020

Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM

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12 December 2020

10.1016/J.MOLMET.2014.12.012

Identifiers

DOI

1 reference

29 September 2017

1 reference

29 September 2017

PubMed publication ID

25737951

1 reference