Evidence for common structural changes in thrombin induced by active-site or exosite binding (Q41971795)

14 October 2017

Evidence for common structural changes in thrombin induced by active-site or exosite binding (English)

1 reference

14 October 2017

Parry MA

1

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14 October 2017

Stone SR

series ordinal

2

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14 October 2017

Hofsteenge J

series ordinal

3

1 reference

14 October 2017

Jackman MP

series ordinal

4

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14 October 2017

language of work or name

English

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publication date

1 March 1993

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14 October 2017

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14 October 2017

290 ( Pt 3)

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14 October 2017

665-670

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

14 October 2017

1 reference

Determination of the operational molarity of solutions of bovine α-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Kinetics of the inhibition of thrombin by hirudin.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Effect of thrombomodulin on the kinetics of the interaction of thrombin with substrates and inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

The structure of a complex of recombinant hirudin and human alpha-thrombin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

The selective inhibition of thrombin by peptides of boroarginine

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Localization of thrombomodulin-binding site within human thrombin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Affinity labeling of lysine-149 in the anion-binding exosite of human alpha-thrombin with an N alpha-(dinitrofluorobenzyl)hirudin C-terminal peptide.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Fluorescence spectrum of barnase: contributions of three tryptophan residues and a histidine-related pH dependence

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Structure of the hirugen and hirulog 1 complexes of alpha-thrombin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Allosteric changes in thrombin's activity produced by peptides corresponding to segments of natural inhibitors and substrates

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Domains specifying thrombin–receptor interaction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Glu-192----Gln substitution in thrombin mimics the catalytic switch induced by thrombomodulin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

A thrombin-based peptide corresponding to the sequence of the thrombomodulin-binding site blocks the procoagulant activities of thrombin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

Intrinsic fluorescence changes and rapid kinetics of the reaction of thrombin with hirudin

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

The COOH-terminal domain of hirudin. An exosite-directed competitive inhibitor of the action of alpha-thrombin on fibrinogen.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1132332

A gas-liquid solid phase peptide and protein sequenator

18 August 2018

1 reference

12 December 2020

Mechanism of the inhibition of alpha-thrombin by hirudin-derived fragments hirudin(1-47) and hirudin(45-65)

1 reference

12 December 2020

The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity

1 reference

12 December 2020

Monocyte chemotaxis: stimulation by specific exosite region in thrombin

1 reference

12 December 2020

Cyclic amides of N alpha-arylsulfonylaminoacylated 4-amidinophenylalanine--tight binding inhibitors of thrombin

1 reference

12 December 2020

Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl++ +) sulfonyl]-l-arginyl)]-2-piperidinecarboxylic acid

1 reference

12 December 2020

Staphylocoagulase-binding region in human prothrombin

1 reference

12 December 2020

Interaction of thrombin with thrombomodulin

1 reference

12 December 2020

Identification of regions of alpha-thrombin involved in its interaction with hirudin

1 reference

12 December 2020

The effect of thrombomodulin on the cleavage of fibrinogen and fibrinogen fragments by thrombin

1 reference

12 December 2020

Preparation and characterization of proteolyzed forms of human α-thrombin

1 reference

12 December 2020

The use of sequence-specific antibodies to identify a secondary binding site in thrombin

1 reference

12 December 2020

Interaction of hirudin with thrombin: identification of a minimal binding domain of hirudin that inhibits clotting activity

1 reference

12 December 2020

Distinct binding sites of Ala48-hirudin1-47 and Ala48-hirudin48-65 on alpha-thrombin

1 reference

12 December 2020

Use of fragments of hirudin to investigate thrombin-hirudin interaction

1 reference

12 December 2020

Human alpha- to zeta-thrombin cleavage occurs with neutrophil cathepsin G or chymotrypsin while fibrinogen clotting activity is retained

1 reference

12 December 2020

Mitogenicity of thrombin and surface alterations on mouse splenocytes

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2900665

1 reference

14 October 2017

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14 October 2017

PubMed publication ID

8457193

1 reference