The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction (Q42152420)

17 October 2017

title

The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction (English)

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identical protein binding

17 October 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Zhiping Wu

1

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17 October 2017

Matthew A Wagner

2

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17 October 2017

Lemin Zheng

3

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17 October 2017

John S Parks

4

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17 October 2017

Jacinto M Shy

5

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17 October 2017

Jonathan D Smith

6

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17 October 2017

Valentin Gogonea

7

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17 October 2017

Stanley L Hazen

8

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17 October 2017

publication date

5 August 2007

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Nature Structural & Molecular Biology

17 October 2017

published in

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17 October 2017

volume

14

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17 October 2017

issue

9

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17 October 2017

page(s)

861-868

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Mechanisms of disease: HDL metabolism as a target for novel therapies

17 October 2017

cites work

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Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse

21 January 2018

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Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial

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HDL as a target in the treatment of atherosclerotic cardiovascular disease

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Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment

21 January 2018

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Formation of dysfunctional high-density lipoprotein by myeloperoxidase.

21 January 2018

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Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis

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CETP inhibitors to increase HDL cholesterol levels

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Effect of torcetrapib on the progression of coronary atherosclerosis

21 January 2018

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Effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia

21 January 2018

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Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease

21 January 2018

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Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities

21 January 2018

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Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages

21 January 2018

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The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport

21 January 2018

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Crystal structure of human apolipoprotein A-I: insights into its protective effect against cardiovascular diseases.

21 January 2018

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Structural analysis of nanoscale self-assembled discoidal lipid bilayers by solid-state NMR spectroscopy.

21 January 2018

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Identification and structural ramifications of a hinge domain in apolipoprotein A-I discoidal high-density lipoproteins of different size

21 January 2018

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Intermolecular contact between globular N-terminal fold and C-terminal domain of ApoA-I stabilizes its lipid-bound conformation: studies employing chemical cross-linking and mass spectrometry.

21 January 2018

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Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL.

21 January 2018

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Apolipoprotein A-I helix 6 negatively charged residues attenuate lecithin-cholesterol acyltransferase (LCAT) reactivity.

21 January 2018

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Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes

21 January 2018

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Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation

21 January 2018

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Truncation of the amino terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation

21 January 2018

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Lecithin:cholesterol acyltransferase deficiency increases atherosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice

21 January 2018

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Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.

21 January 2018

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Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential

21 January 2018

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Compromised LCAT function is associated with increased atherosclerosis

21 January 2018

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Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

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Relationship between the concentration and antiatherogenic activity of high-density lipoproteins

21 January 2018

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HDL cholesterol and protective factors in atherosclerosis

31 March 2020

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Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport.

31 March 2020

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A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein

31 March 2020

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A mass spectrometric determination of the conformation of dimeric apolipoprotein A-I in discoidal high density lipoproteins

31 March 2020

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The use of chemical cross-linking and mass spectrometry to elucidate the tertiary conformation of lipid-bound apolipoprotein A-I.

31 March 2020

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Alteration in apolipoprotein A-I 22-mer repeat order results in a decrease in lecithin:cholesterol acyltransferase reactivity

31 March 2020

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Apolipoprotein A-I assumes a "looped belt" conformation on reconstituted high density lipoprotein

31 March 2020

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Inherited disorders of HDL metabolism and atherosclerosis

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB1284

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Dimensions Publication ID

17 October 2017

1053003435

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