Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors (Q42442206)

31 October 2017

title

Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors (English)

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Stefano Ferrari

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Francesca Di Nunzio

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object named as

Francesca Di Nunzio

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Giulietta Maruggi

2

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Enzo Di Iorio

4

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Valentina Poletti

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Marta Garcia

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Marcela Del Rio

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Michele De Luca

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Fernando Larcher

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publication date

23 September 2008

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volume

16

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issue

12

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page(s)

1977-1985

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The multifaceted adult epidermal stem cell

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cites work

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Long-term renewal of hair follicles from clonogenic multipotent stem cells

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Molecular complexity of the cutaneous basement membrane zone. Revelations from the paradigms of epidermolysis bullosa

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The genetics of human skin diseases

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Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

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Side effects of retroviral gene transfer into hematopoietic stem cells

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The future of gene therapy

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Genotoxicity of retroviral integration in hematopoietic cells.

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Changes in keratin gene expression during terminal differentiation of the keratinocyte

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Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy

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Defining the regulatory factors required for epidermal gene expression

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Identification and dissection of an enhancer controlling epithelial gene expression in skin

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Transcriptional targeting of lentiviral vectors by long terminal repeat enhancer replacement

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Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

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A third-generation lentivirus vector with a conditional packaging system

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A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts

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A preclinical model for the analysis of genetically modified human skin in vivo

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

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Hot spots of retroviral integration in human CD34+ hematopoietic cells

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Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells.

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Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

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Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

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The POU domain factor Skin-1a represses the keratin 14 promoter independent of DNA binding. A possible role for interactions between Skn-1a and CREB-binding protein/p300

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7 January 2021

Novel mechanism of steroid action in skin through glucocorticoid receptor monomers.

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7 January 2021

Negative response elements in keratin genes mediate transcriptional repression and the cross-talk among nuclear receptors

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7 January 2021

Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors

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7 January 2021

A sensitive non-radioactive in situ hybridization method for the detection of chicken IgG γ-chain mRNA: a technique suitable for detecting of variety of mRNAs in tissue sections

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7 January 2021

Identifiers

DOI

10.1038/MT.2008.204

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31 October 2017

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