Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice (Q42957818)

11 November 2017

title

Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice (English)

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11 November 2017

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9

Albert K Groen

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John J P Kastelein

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Carlos L J Vrins

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1

Lily Jakulj

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Frans Stellaard

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Cindy P.A.A. van Roomen

series ordinal

3

object named as

Cindy P van Roomen

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Maud N Vissers

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Jelske N van der Veen

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4

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Cindy Kunne

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6

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11 November 2017

language of work or name

English

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publication date

24 July 2010

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11 November 2017

number of pages

4

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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11 November 2017

volume

584

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issue

16

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page(s)

3625-3628

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Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

11 November 2017

cites work

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Cholesterol-regulated translocation of NPC1L1 to the cell surface facilitates free cholesterol uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Inhibition of intestinal cholesterol absorption by ezetimibe in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.07.035

10.1016/J.FEBSLET.2010.07.035

21 January 2018

Identifiers

DOI

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11 November 2017

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