Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 express (Q43141698)

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scientific article published on 13 February 2009

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English	Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 express	scientific article published on 13 February 2009

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21 January 2020

Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expression (English)

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21 January 2020

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mesenchymal stem cell

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2

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21 January 2020

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Sheik Wisel

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21 January 2020

M Lakshmi Kuppusamy

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I Krishna Mohan

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Simi M Chacko

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21 January 2020

Brian K Rivera

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21 January 2020

Benjamin C Sun

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Kálmán Hideg

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Periannan Kuppusamy

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13 February 2009

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21 January 2020

Journal of Pharmacology and Experimental Therapeutics

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21 January 2020

329

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21 January 2020

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21 January 2020

543-550

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21 January 2020

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11 June 2022

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based on heuristic

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Cardioprotection by HO-4038, a novel verapamil derivative, targeted against ischemia and reperfusion-mediated acute myocardial infarction

1 reference

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Sulfaphenazole protects heart against ischemia-reperfusion injury and cardiac dysfunction by overexpression of iNOS, leading to enhancement of nitric oxide bioavailability and tissue oxygenation

1 reference

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25 May 2018

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25 May 2018

Mesenchymal stem cells and cardiac repair.

1 reference

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25 May 2018

Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation

1 reference

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25 May 2018

Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells

1 reference

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25 May 2018

Differentiation of osteoblasts and osteocytes from mesenchymal stem cells

1 reference

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25 May 2018

Cell-based therapy of myocardial infarction

1 reference

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25 May 2018

Effects of trimetazidine on myocardial preconditioning in anesthetized rats.

1 reference

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25 May 2018

The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

1 reference

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25 May 2018

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672865

25 May 2018

Role of oxidative metabolism on endothelium-dependent vascular relaxation of isolated vessels.

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Mesenchymal stem cells differentiate into an endothelial phenotype, reduce neointimal formation, and enhance endothelial function in a rat vein grafting model

1 reference

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15 August 2018

Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis.

1 reference

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15 August 2018

Hypoxic preconditioning attenuates hypoxia/reoxygenation-induced apoptosis in mesenchymal stem cells.

1 reference

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Trimetazidine protective effect against ischemia-induced susceptibility to ventricular fibrillation in pigs

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Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function.

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Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart

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15 August 2018

Labeling of skeletal myoblasts with a novel oxygen-sensing spin probe for noninvasive monitoring of in situ oxygenation and cell therapy in heart.

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15 August 2018

Attenuation of myocardial ischemia-reperfusion injury by trimetazidine derivatives functionalized with antioxidant properties

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Adverse effects of free fatty acid associated with increased oxidative stress in postischemic isolated rat hearts.

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Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury

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The anti-anginal drug trimetazidine reduces neutrophil-mediated cardiac reperfusion injury

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Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue.

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Trimetazidine protects isolated rat hearts against ischemia-reperfusion injury in an experimental timing-dependent manner.

1 reference

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Protective effect of trimetazidine on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia

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Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase

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Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals

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Direct measurement of free radical generation in isolated rat heart by electron paramagnetic resonance spectroscopy: effect of trimetazidine

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10.1124/JPET.109.150839

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21 January 2020

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