Gabapentin and vigabatrin increase GABA in the human neocortical slice (Q44036802)

29 November 2017

title

Gabapentin and vigabatrin increase GABA in the human neocortical slice (English)

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29 November 2017

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Laura D Errante

1

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29 November 2017

Anne Williamson

series ordinal

2

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29 November 2017

Dennis D Spencer

series ordinal

3

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29 November 2017

Ognen A C Petroff

series ordinal

4

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29 November 2017

language of work or name

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1 May 2002

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29 November 2017

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29 November 2017

volume

49

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29 November 2017

issue

3

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29 November 2017

page(s)

203-210

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Carrier-mediated GABA release activates GABA receptors on hippocampal neurons

29 November 2017

cites work

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Experimental studies of the influence of vigabatrin on the GABA system

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Topiramate increases cerebral GABA in healthy humans

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Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain

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Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brain

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The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA).

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Epilepsy and γ-Aminobutyric Acid-Mediated Inhibition

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GABA uptake and heterotransport are impaired in the dentate gyrus of epileptic rats and humans with temporal lobe sclerosis

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7 January 2021

Metabolic assessment of a neuron-enriched fraction of rat cerebrum using high-resolution 1H and 13C NMR spectroscopy

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Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain

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Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin

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7 January 2021

Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures

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Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures

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Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients

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7 January 2021

Topiramate rapidly raises brain GABA in epilepsy patients

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7 January 2021

Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt

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A summary of mechanistic hypotheses of gabapentin pharmacology

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Lack of correlation between neuronal hyperexcitability and electrocorticographic responsiveness in epileptogenic human neocortex

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7 January 2021

GABA transaminase inhibition induces spontaneous and enhances depolarization-evoked GABA efflux via reversal of the GABA transporter.

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7 January 2021

10.1016/S0920-1211(02)00034-7

Identifiers

DOI

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29 November 2017

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