IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells (Q44536385)

3 December 2017

title

IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells (English)

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3 December 2017

Satoru Osuka

1

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3 December 2017

Oltea Sampetrean

2

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3 December 2017

Takatsune Shimizu

3

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3 December 2017

Isako Saga

4

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3 December 2017

Nobuyuki Onishi

5

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3 December 2017

Eiji Sugihara

6

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3 December 2017

Jun Okubo

7

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3 December 2017

Satoshi Fujita

8

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3 December 2017

Shingo Takano

9

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3 December 2017

Akira Matsumura

10

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3 December 2017

Hideyuki Saya

11

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3 December 2017

publication date

1 April 2013

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3 December 2017

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3 December 2017

volume

31

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3 December 2017

issue

4

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3 December 2017

page(s)

627-640

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

3 December 2017

cites work

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

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CD24(-/low) stem-like breast cancer marker defines the radiation-resistant cells involved in memorization and transmission of radiation-induced genomic instability

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Hedgehog/GLI1 regulates IGF dependent malignant behaviors in glioma stem cells

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Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition

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Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells

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Feedback mechanisms promote cooperativity for small molecule inhibitors of epidermal and insulin-like growth factor receptors

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Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase

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Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade

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Role of IGF-1 receptor in radiation response.

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High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

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Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.

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Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells

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c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.

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Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

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Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

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Presence of MHC-I and B-7 molecules in rat and human glioma cells expressing antisense IGF-I mRNA.

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Regulation of FoxO transcription factors by acetylation and protein-protein interactions

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Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

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Integrating opposing signals toward Forkhead box O.

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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

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Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta

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Radiation-induced bystander signaling pathways in human fibroblasts: a role for interleukin-33 in the signal transmission

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Redundancy of radioresistant signaling pathways originating from insulin-like growth factor I receptor

21 January 2018

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Lentivirus-mediated RNAi knockdown of insulin-like growth factor-1 receptor inhibits growth, reduces invasion, and enhances radiosensitivity in human osteosarcoma cells

21 January 2018

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Insulin-like growth factor-I receptor signaling blockade combined with radiation

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SiRNA-mediated IGF-1R inhibition sensitizes human colon cancer SW480 cells to radiation

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Modulation of response to radiation of human lung cancer cells following insulin-like growth factor 1 receptor inactivation

21 January 2018

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Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors

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Cancer Stem Cells and Radiotherapy: New Insights Into Tumor Radioresistance

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1328

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3 December 2017

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