Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism (Q44801726)

6 December 2017

title

Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism (English)

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6 December 2017

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13

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12

Kaj Blennow

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7

Margaret Gatz

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3

Juni Palmgren

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Boo Johansson

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Nigel J Cairns

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Anthony J Brookes

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Nancy L Pedersen

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1

Hagit Katzov

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Katy Chalmers

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Niels Andreasen

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Gordon K Wilcock

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Seth Love

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Jonathan A Prince

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publication date

1 April 2004

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6 December 2017

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6 December 2017

volume

23

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issue

4

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6 December 2017

page(s)

358-367

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Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease

6 December 2017

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Beta-amyloid (Abeta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease

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Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

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Of replications and refutations: the status of Alzheimer's disease genetic research

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Results of a high-resolution genome screen of 437 Alzheimer's disease families

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Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

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APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein

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Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees

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Further evidence for role of a promoter variant in the TNFRSF6 gene in Alzheimer disease.

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study

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Statins and the risk of dementia

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Haplotype tagging for the identification of common disease genes

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A full genome scan for late onset Alzheimer's disease.

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Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease

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Haplotypes extending across ACE are associated with Alzheimer's disease

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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion

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Elevated low-density lipoprotein in Alzheimer's disease correlates with brain abeta 1-42 levels

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7 January 2021

Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease.

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7 January 2021

Susceptibility locus for Alzheimer's disease on chromosome 10.

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7 January 2021

Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms

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7 January 2021

Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation

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7 January 2021

Genetic variation in a haplotype block spanningIDE influences Alzheimer disease

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7 January 2021

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

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7 January 2021

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

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7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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7 January 2021

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol

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7 January 2021

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

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7 January 2021

The accuracy of statistical methods for estimation of haplotype frequencies: an example from the CD4 locus

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7 January 2021

ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease

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7 January 2021

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

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7 January 2021

Beta blockade during and after myocardial infarction: an overview of the randomized trials

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7 January 2021

ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

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7 January 2021

Identifiers

DOI

10.1002/HUMU.20012

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6 December 2017

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