Luminal cysteine-proteases degrade colonic tight junction structure and are responsible for abdominal pain in constipation-predominant IBS. (Q45189883)

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1 March 2020

title

Luminal cysteine-proteases degrade colonic tight junction structure and are responsible for abdominal pain in constipation-predominant IBS (English)

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1

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Mathilde Leveque

4

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Moïse Coëffier

7

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author name string

Laurent Ferrier

2

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Valerie Bézirard

3

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Helene Eutamène

5

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Afifa Ait-Belgnaoui

6

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Philippe Ducrotté

8

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Richárd Róka

9

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Orsolya Inczefi

10

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Krisztina Gecse

11

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András Rosztóczy

12

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Tamás Molnár

13

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Tamar Ringel-Kulka

14

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Yehuda Ringel

15

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Thierry Piche

16

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Vassilia Theodorou

17

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Tibor Wittmann

18

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Lionel Bueno

19

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language of work or name

English

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publication date

28 May 2013

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The American Journal of Gastroenterology

1 March 2020

published in

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volume

108

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issue

8

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page(s)

1322-1331

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Irritable bowel syndrome: epidemiology, natural history, health care seeking and emerging risk factors

1 March 2020

cites work

1 reference

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Altered rectal perception is a biological marker of patients with irritable bowel syndrome.

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Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators.

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A Pilot Study of Fecal Serine-Protease Activity: A Pathophysiologic Factor in Diarrhea-Predominant Irritable Bowel Syndrome

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Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity

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Entamoeba histolytica cysteine proteinases with interleukin-1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis

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Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions

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Increased proteasome-mediated degradation of occludin in irritable bowel syndrome.

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Irreversible inhibitors of serine, cysteine, and threonine proteases

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

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Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase

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Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome

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Altered protease signalling in the gut: a novel pathophysiological factor in irritable bowel syndrome

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An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota.

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Emerging roles for cysteine proteases in human biology

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Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome.

21 January 2018

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Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome

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Bacterial proteinases as targets for the development of second-generation antibiotics

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The global cysteine peptidase landscape in parasites

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Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice

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Luminal cathepsin g and protease-activated receptor 4: a duet involved in alterations of the colonic epithelial barrier in ulcerative colitis

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Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome

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Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario

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Abnormal intestinal permeability in subgroups of diarrhea-predominant irritable bowel syndromes

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Increased gastrointestinal permeability and gut inflammation in children with functional abdominal pain and irritable bowel syndrome

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Lower functional gastrointestinal disorders: evidence of abnormal colonic transit in a 287 patient cohort

21 January 2018

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Multifunctional strands in tight junctions

21 January 2018

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Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model

21 January 2018

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Mechanism of colonic permeation of inulin: is rat colon more permeable than small intestine?

21 January 2018

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Evaluation of intestinal absorption and mucosal toxicity using two promoters. II. Rat instillation and perfusion studies

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Identifiers

DOI

10.1038/AJG.2013.152

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release_ibnmstluhfdyfgoi5vpldl3b24

1 March 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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