Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice (Q45375432)

13 December 2017

title

Adipose tissue hypoxia induces inflammatory M1 polarity of macrophages in an HIF-1α-dependent and HIF-1α-independent manner in obese mice (English)

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13 December 2017

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S Fujisaka

1

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13 December 2017

I Usui

2

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13 December 2017

M Ikutani

3

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13 December 2017

A Aminuddin

4

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13 December 2017

A Takikawa

5

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13 December 2017

K Tsuneyama

6

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13 December 2017

A Mahmood

7

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13 December 2017

N Goda

8

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13 December 2017

Y Nagai

9

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13 December 2017

K Takatsu

10

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13 December 2017

K Tobe

11

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13 December 2017

language of work or name

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15 March 2013

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13 December 2017

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13 December 2017

volume

56

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13 December 2017

issue

6

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13 December 2017

page(s)

1403-1412

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Inflammation and metabolic disorders

13 December 2017

cites work

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Obesity is associated with macrophage accumulation in adipose tissue

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective

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Monocyte and macrophage heterogeneity

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The chemokine system in diverse forms of macrophage activation and polarization

21 January 2018

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Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice.

21 January 2018

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Macrophage polarization and insulin resistance: PPARgamma in control

21 January 2018

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

21 January 2018

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PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

21 January 2018

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Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.

21 January 2018

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Adipose tissue remodeling and obesity

21 January 2018

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Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

21 January 2018

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Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

21 January 2018

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Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

21 January 2018

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Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes

21 January 2018

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Blood Flow through Human Adipose Tissue Determined with Radioactive Xenon

21 January 2018

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Obesity decreases perioperative tissue oxygenation

21 January 2018

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Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

21 January 2018

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Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss

21 January 2018

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Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue

21 January 2018

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Intestinal, adipose, and liver inflammation in diet-induced obese mice.

21 January 2018

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Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice

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Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response

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Role of hypoxia in obesity-induced disorders of glucose and lipid metabolism in adipose tissue

21 January 2018

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Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

21 January 2018

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21 January 2018

Sensing necrotic cells

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Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

21 January 2018

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IKK-beta links inflammation to obesity-induced insulin resistance

21 January 2018

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21 January 2018

Hypoxia and inflammation

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

21 January 2018

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Rates of skeletal muscle and adipose tissue glycerol release in nonobese and obese subjects.

21 January 2018

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Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance.

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Adipose tissue vascularization: its role in chronic inflammation

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Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis

21 January 2018

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Differences in adipocytokines and fatty acid composition between two adipocyte fractions of small and large cells in high-fat diet-induced obese mice.

21 January 2018

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Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

21 January 2018

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12 December 2020

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

12 December 2020

Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels

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12 December 2020

Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid

1 reference

12 December 2020

Telmisartan improves insulin resistance and modulates adipose tissue macrophage polarization in high-fat-fed mice

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12 December 2020

Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids

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12 December 2020

10.1007/S00125-013-2885-1

Identifiers

DOI

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Dimensions Publication ID

13 December 2017

1049185943

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