Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC. (Q48605678)

13 February 2018

title

Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC. (English)

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13 February 2018

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Tatsushi Igaki

1

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13 February 2018

Yuki Yamamoto-Goto

2

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13 February 2018

Naoko Tokushige

3

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13 February 2018

Hiroshi Kanda

4

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13 February 2018

Masayuki Miura

5

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13 February 2018

language of work or name

English

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publication date

13 May 2002

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13 February 2018

Journal of Biological Chemistry

published in

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13 February 2018

volume

277

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13 February 2018

issue

26

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13 February 2018

page(s)

23103-23106

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13 February 2018

Programmed cell death in animal development

cites work

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IAP family proteins--suppressors of apoptosis

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

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Cell death regulation in Drosophila: conservation of mechanism and unique insights

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Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

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The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

21 January 2018

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Drob-1, a Drosophila member of the Bcl-2/CED-9 family that promotes cell death

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Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: implicated mechanisms for caspase activation

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Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator

21 January 2018

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The Drosophila caspase DRONC is regulated by DIAP1

21 January 2018

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DRONC, an ecdysone-inducible Drosophila caspase

21 January 2018

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The role of ARK in stress-induced apoptosis in Drosophila cells

21 January 2018

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Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark

21 January 2018

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21 January 2018

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Cell Death in Development

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C200222200

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13 February 2018

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13 February 2018