Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1. (Q51408849)

2 July 2019

title

Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1. (English)

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2 July 2019

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2

Alexander Wlodawer

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2 July 2019

author name string

Di Zhang

series ordinal

1

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2 July 2019

Jacek Lubkowski

series ordinal

3

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2 July 2019

language of work or name

English

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publication date

7 October 2016

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2 July 2019

Journal of Molecular Biology

published in

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2 July 2019

volume

428

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issue

23

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page(s)

4651-4668

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Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

cites work

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Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

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Automated protein model building combined with iterative structure refinement

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Biological activity of interleukins-28 and -29: comparison with type I interferons

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The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling

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Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation

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Crystal Structure of the FERM-SH2 Module of Human Jak2.

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Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

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10.1016/J.JMB.2016.10.005

Identifiers

DOI

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2 July 2019

PMC publication ID

6288811

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2 July 2019

PubMed publication ID

27725180

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2 July 2019