The Ron oncogenic activity induced by the MEN2B-like substitution overcomes the requirement for the multifunctional docking site. (Q53404270)

14 May 2018

title

The Ron oncogenic activity induced by the MEN2B-like substitution overcomes the requirement for the multifunctional docking site. (English)

1 reference

14 May 2018

author name string

M M Santoro

1

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14 May 2018

L Penengo

2

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14 May 2018

S Orecchia

3

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14 May 2018

M Cilli

4

1 reference

14 May 2018

G Gaudino

5

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14 May 2018

language of work or name

English

0 references

publication date

1 October 2000

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14 May 2018

published in

Oncogene

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14 May 2018

volume

19

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14 May 2018

issue

45

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14 May 2018

page(s)

5208-5211

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14 May 2018

Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

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Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B

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Activating mutations in the Met receptor overcome the requirement for autophosphorylation of tyrosines crucial for wild type signaling

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Macrophage-stimulating protein activates Ras by both activation and translocation of SOS nucleotide exchange factor

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Oncogenic activation of the PDGF beta receptor by the transmembrane domain of p185neu*.

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Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

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Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

21 January 2018

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Constitutive activation of the RON gene promotes invasive growth but not transformation

21 January 2018

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Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor

21 January 2018

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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Identification of the ron gene product as the receptor for the human macrophage stimulating protein

21 January 2018

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A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

21 January 2018

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MET(PRC) mutations in the Ron receptor result in upregulation of tyrosine kinase activity and acquisition of oncogenic potential

21 January 2018

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Neu receptor dimerization

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Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm

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7 January 2021

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Identifiers

DOI

10.1038/SJ.ONC.1203819

1 reference

14 May 2018

1 reference

14 May 2018