Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS). (Q54660067)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS).	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Metabolite elucidation of the Hsp90 inhibitor SNX-2112 using ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS). (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

author name string

Wei Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Hongming Liu

2

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Hua Sun

3

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Dong Dong

4

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Zhiguo Ma

5

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Yifei Wang

6

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Baojian Wu

7

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

language of work or name

0 references

publication date

5 November 2013

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

44

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

5

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

455-464

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Current and future trends in the application of HPLC-MS to metabolite-identification studies

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Pharmacokinetics, metabolism, and excretion of the antiviral drug arbidol in humans

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Metabolism and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor apatinib in humans.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Metabolism of flumatinib, a novel antineoplastic tyrosine kinase inhibitor, in chronic myelogenous leukemia patients

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cells

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Generic dealkylation: a tool for increasing the hit-rate of metabolite rationalization, and automatic customization of mass defect filters

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Strategies for dealing with metabolite elucidation in drug discovery and development

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Heat-shock protein 90 inhibitors as novel cancer chemotherapeutics - an update

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Structure and ligand-based design of P-glycoprotein inhibitors: a historical perspective

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Three decades of P-gp inhibitors: skimming through several generations and scaffolds.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

SNX-2112, a novel Hsp90 inhibitor, induces G2/M cell cycle arrest and apoptosis in MCF-7 cells

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

'All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS.

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Quantitation of small molecules using high-resolution accurate mass spectrometers - a different approach for analysis of biological samples

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Glucuronidation of dihydrotestosterone and trans-androsterone by recombinant UDP-glucuronosyltransferase (UGT) 1A4: evidence for multiple UGT1A4 aglycone binding sites

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2013.853849

21 January 2018

Identifiers

10.3109/00498254.2013.853849

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 June 2018

http://europepmc.org/abstract/MED/24191862

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q54660067&oldid=1727133287"