HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition. (Q55002157)

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scientific article published on 30 April 2018

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English	HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition.	scientific article published on 30 April 2018

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25 March 2020

HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition (English)

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25 March 2020

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25 March 2020

Céline Bressollette-Bodin

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25 March 2020

Mathilde Allard

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25 March 2020

Beatrice Charreau

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25 March 2020

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Nathalie Gérard

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25 March 2020

Magali Giral

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25 March 2020

Pierrick Guérif

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25 March 2020

Audrey Rodallec

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25 March 2020

Romain Oger

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25 March 2020

Tiphaine Parrot

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25 March 2020

Anne Cesbron-Gautier

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25 March 2020

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30 April 2018

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25 March 2020

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25 March 2020

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25 March 2020

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25 March 2020

e1007041

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25 March 2020

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Creative Commons Attribution 4.0 International

30 April 2018

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0 references

Definitions of Cytomegalovirus Infection and Disease in Transplant Patients for Use in Clinical Trials.

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T cell responses to cytomegalovirus

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16 June 2018

A new perspective of the structural complexity of HCMV-specific T-cell responses

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PD-1 expression conditions T cell avidity within an antigen-specific repertoire

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Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.

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16 June 2018

The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch

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Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response

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16 June 2018

HLA-E: Presentation of a Broader Peptide Repertoire Impacts the Cellular Immune Response-Implications on HSCT Outcome

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16 June 2018

The Presence of HLA-E-Restricted, CMV-Specific CD8+ T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection

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16 June 2018

Molecular characterization of HCMV-specific immune responses: Parallels between CD8(+) T cells, CD4(+) T cells, and NK cells

1 reference

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16 June 2018

Human CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.

1 reference

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16 June 2018

Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options

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16 June 2018

IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion

1 reference

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16 June 2018

Cytomegalovirus infections in solid organ transplantation: a review

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16 June 2018

Multimer monitoring of CMV-specific T cells in research and in clinical applications.

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CMV: Prevention, Diagnosis and Therapy

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16 June 2018

Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells.

1 reference

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16 June 2018

HLA-E-restricted cross-recognition of allogeneic endothelial cells by CMV-associated CD8 T cells: a potential risk factor following transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945056

16 June 2018

State-of-the-art monitoring of cytomegalovirus-specific cell-mediated immunity after organ transplant: a primer for the clinician

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16 June 2018

T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection

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16 June 2018

Human cytomegalovirus UL40 signal peptide regulates cell surface expression of the NK cell ligands HLA-E and gpUL18

1 reference

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16 June 2018

Complications, diagnosis, management, and prevention of CMV infections: current and future

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16 June 2018

Regulation of self-tolerance by Qa-1-restricted CD8(+) regulatory T cells

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16 June 2018

The emerging role of cytomegalovirus in driving immune senescence: a novel therapeutic opportunity for improving health in the elderly

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16 June 2018

The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress

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16 June 2018

The emerging role of HLA-E-restricted CD8+ T lymphocytes in the adaptive immune response to pathogens and tumors

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16 June 2018

Tricks with tetramers: how to get the most from multimeric peptide-MHC.

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16 June 2018

The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity.

1 reference

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16 June 2018

CD8 T-cell-based immunotherapy of cytomegalovirus infection: "proof of concept" provided by the murine model

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16 June 2018

CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

1 reference

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16 June 2018

Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region

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16 June 2018

Structural basis for a major histocompatibility complex class Ib-restricted T cell response

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16 June 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

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16 June 2018

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

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CD8(+) T-cell immunity to cytomegalovirus

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16 June 2018

HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes

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16 June 2018

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition

1 reference

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16 June 2018

Definitive high resolution typing of HLA-E allelic polymorphisms: Identifying potential errors in existing allele data

1 reference

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HLA-E allelic variants. Correlating differential expression, peptide affinities, crystal structures, and thermal stabilities

1 reference

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16 June 2018

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1 reference

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16 June 2018

UL40-mediated NK evasion during productive infection with human cytomegalovirus.

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The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.

1 reference

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16 June 2018

Cutting edge: the human cytomegalovirus UL40 gene product contains a ligand for HLA-E and prevents NK cell-mediated lysis

1 reference

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16 June 2018

Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40.

1 reference

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16 June 2018

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1 reference

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16 June 2018

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1 reference

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16 June 2018

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1 reference

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29 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29709038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability of UL18, UL40, UL111a and US3 immunomodulatory genes among human cytomegalovirus clinical isolates from renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/29709038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Rapid Induction of HLA-E Is Essential for the Survival of Antigen-Activated Naive CD4 T Cells from Attack by NK Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29709038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytomegalovirus in solid organ transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29709038

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PPAT.1007041

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25 March 2020

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25 March 2020

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25 March 2020

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