Active site-directed protein regulation (Q56879499)

Intrasteric regulation of protein kinases and phosphatases

21 January 2018

1 reference

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

21 January 2018

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Structural basis for activation of the titin kinase domain during myofibrillogenesis

21 January 2018

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Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I

21 January 2018

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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

21 January 2018

1 reference

Crystal structure of the tyrosine kinase domain of the human insulin receptor

21 January 2018

1 reference

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

21 January 2018

1 reference

Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

21 January 2018

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

21 January 2018

1 reference

The structure and mechanism of protein phosphatases: insights into catalysis and regulation

21 January 2018

1 reference

Crystal structure of the tyrosine phosphatase SHP-2

21 January 2018

1 reference

Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

21 January 2018

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Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-alpha

21 January 2018

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Switching signals on or off by receptor dimerization

21 January 2018

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Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes

21 January 2018

1 reference

Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

21 January 2018

1 reference

Structure of bovine trypsinogen at 1.9 Å resolution

21 January 2018

1 reference

Natural protein proteinase inhibitors and their interaction with proteinases

21 January 2018

1 reference

Structural basis of autoregulation of phenylalanine hydroxylase

21 January 2018

1 reference

Chloroplast NADP-malate dehydrogenase: structural basis of light-dependent regulation of activity by thiol oxidation and reduction

21 January 2018

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Structural basis for light activation of a chloroplast enzyme: the structure of sorghum NADP-malate dehydrogenase in its oxidized form

21 January 2018

1 reference

Distinct phosphorylation signals converge at the catalytic center in glycogen phosphorylases

21 January 2018

1 reference

Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha

21 January 2018

1 reference

Structure of importin-beta bound to the IBB domain of importin-alpha

21 January 2018

1 reference

The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence

21 January 2018

1 reference

Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

21 January 2018

1 reference

Three-dimensional structure of the tyrosine kinase c-Src

21 January 2018

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Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

1 reference

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

21 January 2018

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Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

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Principles of CDK regulation

21 January 2018

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Regulation of an enzyme by phosphorylation at the active site

21 January 2018

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NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction

21 January 2018

1 reference

High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70

21 January 2018

1 reference

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

21 January 2018

1 reference

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

Insights into autoregulation from the crystal structure of twitchin kinase

21 January 2018

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Ca2+ /S100 regulation of giant protein kinases

21 January 2018

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From phosphorylase to phosphorylase kinase

21 January 2018

1 reference

7 January 2021

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus

1 reference

7 January 2021

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import

1 reference

7 January 2021

The protein kinase domain of the ANP receptor is required for signaling

1 reference

7 January 2021