Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy (Q57239820)

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12 March 2020

title

Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy (English)

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12 March 2020

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1

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Núria Planell

2

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12 March 2020

Juan J Lozano

4

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Ingrid Ordas

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Manel Esteller

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Julian Panes

11

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Azucena Salas

12

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author name string

Radhika Kajekar

3

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Isabella Dotti

6

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M Carme Masamunt

8

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Harsukh Parmar

9

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Elena Ricart

10

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language of work or name

English

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publication date

3 April 2014

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volume

64

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issue

2

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12 March 2020

page(s)

233-242

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Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease: an update

12 March 2020

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Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data

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Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial

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Late Crohn's disease patients present an increase in peripheral Th17 cells and cytokine production compared with early patients.

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Development and validation of an endoscopic index of the severity for Crohn's disease: a prospective multicentre study. Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du Tube Digestif (GETAID)

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Mucosal gene expression of cell adhesion molecules, chemokines, and chemokine receptors in patients with inflammatory bowel disease before and after infliximab treatment.

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Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease.

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PTPN2 is associated with Crohn's disease and its expression is regulated by NKX2-3.

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Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment

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Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations

21 January 2018

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Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis

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A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

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TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer

21 January 2018

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Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-alpha-responsive elements.

21 January 2018

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The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein

21 January 2018

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Heparin attenuates TNF-alpha induced inflammatory response through a CD11b dependent mechanism

21 January 2018

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TNF-α induces expression of urokinase-type plasminogen activator and β-catenin activation through generation of ROS in human breast epithelial cells

21 January 2018

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Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy

21 January 2018

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Normalization of mucosal cytokine gene expression levels predicts long-term remission after discontinuation of anti-TNF therapy in Crohn's disease

21 January 2018

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Anti-tumour necrosis factor therapy enhances mucosal healing through down-regulation of interleukin-21 expression and T helper type 17 cell infiltration in Crohn's disease.

21 January 2018

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Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

21 January 2018

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Magnetic resonance imaging for evaluation of Crohn's disease: validation of parameters of severity and quantitative index of activity

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Biomarkers of Therapeutic Response in the IL-23 Pathway in Inflammatory Bowel Disease

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Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2

21 January 2018

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Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

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Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study

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10.1136/GUTJNL-2013-306518

21 January 2018

Identifiers

DOI

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12 March 2020

1 reference