Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system (Q72201126)

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scientific article published on 01 January 1994

Language	Label	Description	Also known as
English	Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system	scientific article published on 01 January 1994

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7734108%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7734108%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

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T Takahashi

1

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24 October 2019

Y Deng

2

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24 October 2019

W Maruyama

3

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24 October 2019

P Dostert

4

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24 October 2019

M Kawai

5

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24 October 2019

M Naoi

6

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24 October 2019

publication date

1 January 1994

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24 October 2019

98

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24 October 2019

2

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24 October 2019

107-118

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24 October 2019

Endogenous synthesis of N-methylsalsolinol, an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in rat brain during in vivo microdialysis with salsolinol, as demonstrated by gas chromatography-mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous synthesis of N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of N-methylisoquinolinium ion, in the brains of primates with parkinsonism after systemic administration of 1,2,3,4-tetrahydroisoquinoline

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat brain salsolinol and blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methylation of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, (R)-salsolinol, in rat brains: in vivo microdialysis study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An endogenous substance of the brain, tetrahydroisoquinoline, produces parkinsonism in primates with decreased dopamine, tyrosine hydroxylase and biopterin in the nigrostriatal regions

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective release of serotonin by endogenous alkaloids, 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines, (R)- and (S)salsolinol, in the rat striatum; in vivo microdialysis study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ion

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel toxins and Parkinson's disease: N-methylation and oxidation as metabolic bioactivation of neurotoxin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salsolinol and catecholamines in human brain and their relation to alcoholism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of N-methyl-1,2,3,4-tetrahydroisoquinoline into the N-methyl-isoquinolinium ion by monoamine oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methylated tetrahydroisoquinolines as dopaminergic neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of food intake on the enantiomeric composition of urinary salsolinol in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of 1,2(N)-dimethyl-6,7-dihydroxy-isoquinolinium ion to melanin: effects of ferrous and ferric ion on the binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human clonal cell line model of differentiating neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkaloids in mammalian tissues. 2. Synthesis of (+)- and (-)-1-substituted-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methylisoquinolinium ion as an inhibitor of tyrosine hydroxylase, aromatic l-amino acid decarboxylase and monoamine oxidase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of tetrahydroisoquinoline and 2-methyl-tetrahydroquinoline in parkinsonian and normal human brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of salsolinol, a tetrahydroisoquinoline alkaloid, in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pargyline Prevents MPTP-Induced Parkinsonism in Primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/7734108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01277014

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7734108%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7734108%20AND%20SRC:MED&resulttype=core&format=json

24 October 2019

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