Intestinal alphabeta T cells of symptomatic celiac disease patients show oligoclonal TCRBV repertoire but polyclonal rearrangement patterns (Q73480234)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689114%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Intestinal alphabeta T cells of symptomatic celiac disease patients show oligoclonal TCRBV repertoire but polyclonal rearrangement patterns (English)

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4 November 2019

author name string

A Balas

1

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4 November 2019

M D Garcia-Novo

2

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4 November 2019

J Martinez

3

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4 November 2019

F García-Sánchez

4

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4 November 2019

S Santos

5

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4 November 2019

J L Vicario

6

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4 November 2019

publication date

1 March 2000

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4 November 2019

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4 November 2019

volume

61

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4 November 2019

issue

3

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4 November 2019

page(s)

247-254

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4 November 2019

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Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue')

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Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer

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Absolute linkage of celiac disease and dermatitis herpetiformis to HLA-DQ

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Production of antiendomysial antibodies after in-vitro gliadin challenge of small intestine biopsy samples from patients with coeliac disease

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Activated T lymphocytes in the celiac lesion: non-proliferative activation (CD25) of CD4+ alpha/beta cells in the lamina propria but proliferation (Ki-67) of alpha/beta and gamma/delta cells in the epithelium

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Intraepithelial T cells of the TcR gamma/delta+ CD8- and V delta 1/J delta 1+ phenotypes are increased in coeliac disease

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Gliadin-specific, HLA-DQ(alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients

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T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8.

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T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules

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Gliadin-specific T cell responses in peripheral blood of healthy individuals involve T cells restricted by the coeliac disease associated DQ2 heterodimer

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The in vitro response to human fibroblast-derived extracellular matrix proteins is restricted by specific HLA class II genes. Relevance for coeliac disease

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Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

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Selection for T-cell receptor Vβ–Dβ–Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis

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Common T cell receptor clonotype in lacrimal glands and labial salivary glands from patients with Sjögren's syndrome

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The V-region disease hypothesis: evidence from autoimmune encephalomyelitis

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T lymphocytes in human gut epithelium preferentially express the alpha/beta antigen receptor and are often CD45/UCHL1-positive

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Subsets of CD3+ (T cell receptor α/β or γ/δ) and CD3− lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood

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Distribution of dominant T cell receptor beta chains in human intestinal mucosa

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Comparisons of T cell receptor (TCR) V beta repertoires of lamina propria and peripheral blood lymphocytes with respect to frequency and oligoclonality

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Oligoclonality of human intestinal intraepithelial T cells

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Serotyping for homotransplantation. 18. Refinement of microdroplet lymphocyte cytotoxicity test

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Histological changes in small bowel mucosa induced by gliadin sensitive T lymphocytes can be blocked by anti-interferon gamma antibody

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Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma

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Heterogeneous reactivity patterns of HLA-DQ-restricted, small intestinal T-cell clones from patients with celiac disease

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10.1016/S0198-8859(99)00152-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10689114%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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